电刺激诱发瞬目反射和脑干听觉诱发电位在多发性硬化诊断中的作用  

Electrically triggered blink reflex and brainstem auditory evoked potential in the diagnosis of multiple sclerosis

作　　者：胡学强[1] 李津[1] 

机构地区：[1]中山大学附属第三医院神经病学科,广州510630

出　　处：《中华神经科杂志》2004年第5期417-419,共3页Chinese Journal of Neurology

摘　　要：目的　探讨瞬目反射 (BR)在多发性硬化 (MS)诊断中的价值。方法　对 32例确诊MS患者分别进行BR和脑干听觉诱发电位 (BAEP)检测。结果　MS组BR检测在有脑干症状组和无脑干症状组的脑干损害检出率分别为 85 7%和 5 0 0 % ;BR检测对MS组患者Ⅴ、Ⅶ脑神经损害的异常检出率均为 2 1 9% ;BAEP检测在有脑干症状组和无脑干症状组的脑干损害检出率分别为 71 4 %和4 4 4 % ;BR、BAEP及二者联合检测检出MS患者脑干损害的阳性率分别为 6 5 6 %、5 6 3%和75 0 %。结论　BR能检出MS患者脑干、三叉神经及面神经的亚临床病灶 ;BR与BAEP联合检测更易于发现脑干亚临床病灶 。Objective To explore the value of blink reflex (BR) and brainstem auditory evoked potential (BAEP) in the diagnosis of multiple sclerosis (MS). Methods Totally 20 normal persons and 32 MS patients were examined with BR and BAEP respectively.Results 32 MS patients were divided into two groups according to the abnormalities localized to the brainstem: the symptomatic group and the asymptomatic group. The abnormal rates of BR in two groups were 85.7% and 50.0% respectively. The abnormal rates of BAEP in the two groups were 71.4% and 44.4% respectively. The abnormal rates of BR in Ⅴand Ⅶ cranial nerves were both 21.9%. The abnormal rates of BR,BAEP,BR and BAEP in finding out lesions of brainstem were 65.6%,56.3% and 75.0% respectively.Conclusions Subclinical lesions in brainstem, Ⅴand Ⅶ cranial nerves were demonstrated by BR. The combined abnormal rate of BR and BAEP was higher than either test alone.

关 键 词：诊断 脑干 MS BAEP 患者 瞬目反射 多发性硬化 发现 电刺激 损害 

分 类 号：R744.51[医药卫生—神经病学与精神病学] R743[医药卫生—临床医学]