广东省社区人群慢性便秘的流行病学研究  

A community population-based epidemiologic study of chronic constipation in Guangdong province

作　　者：熊理守[1] 陈旻湖[1] 陈惠新[2] 许岸高[2] 王伟岸[1] 胡品津[1] 

机构地区：[1]中山大学附属第一医院消化内科,广州510080 [2]广东省惠州市中心医院消化内科

出　　处：《中华消化杂志》2004年第8期488-491,共4页Chinese Journal of Digestion

摘　　要：目的　探讨广东省社区人群慢性便秘的患病情况及对生存质量的影响。方法　用整群、分层、随机抽样的方法对广州市、惠州市和农村地区常住人口中 18～ 80岁的居民进行问卷调查。结果　共 3931人接受便秘相关问题调查 ,其中男 1795人 ,女 2 136人 ;平均年龄为 (4 2 .7± 14 .1)岁。共检出符合罗马Ⅱ标准的慢性便秘 15 9名 ,患病率为 4 .0 % ,其中男性患病率为 3.6 % ,女性为 4 .4 % ;按 2 0 0 0年第 5次全国人口普查结果进行年龄、性别标准化后的患病率为 3.6 % ;患病率有随着年龄的增加而升高的趋势。经多因素分析后发现 ,农村居民 (OR =1.6 7)、体重指数低于 18.5 (OR =2 .15 )、诉工作压力大且难以承受者 (OR =3.0 8)、文化程度低 (OR =2 .16 )及合并有肠易激综合征者 (OR =2 .81)更倾向于发生慢性便秘。与非慢性便秘人群比较 ,慢性便秘人群的生存质量除情感职能 (P =0 .0 97)外 ,生理机能、生理职能、社会功能、躯体疼痛、精力、一般状况、精神健康和健康变化均有明显下降 (P <0 .0 5 )。结论　慢性便秘在广东省社区人群中是一种常见病 ,尤其多见于老年人 ,并对患者的生存质量有明显影响 ;工作压力大等为可能的危险因素。Objective To investigate prevalence of chronic constipation in Guangdong province and its impact on health-related quality of life (HRQOL). Methods A questionnaire survey was conducted among permanent inhabitants aged 18-80 years in Guangdong province by randomizing clustered sampling under stratification of urban and suburban areas. The impact of symptoms on HRQOL was evaluated using a well-standardized measure, the SF-36. Results A total of 3931 residents (male 1795, female 2136) were investigated. Mean age among the responders was (42.7±14.1) years old. The prevalence of chronic constipation in Guangdong province is 4.0% according to RomeⅡcriteria. The age-and gender-specific standardized constipation rates after gender and age adjustment was 3.6%. The prevalence was increasing with age. A body mass index <18.5 (OR=2.15), living in rural areas(OR=1.67), higher working burden (OR=3.08),primary-school education or illiterate (OR=2.16) and accompanied by irritable bowel syndrome symptoms (OR=2.81) were independently associated with chronic constipation (P<0.05). Patients with chronic constipation had significantly poorer HRQOL than controls did. Conclusion Chronic constipation is a common disorder in Guangdong province which exerted a negative impact of HRQOL on sufferers.

关 键 词：广东 社区人群 慢性便秘 流行病学 精神健康 

分 类 号：R574.62[医药卫生—消化系统]