子宫内膜间质肉瘤16例临床分析  

Clinical analysis of 16 cases of endometrial stromal sarcoma.

作　　者：王彦莹[1] 

机构地区：[1]天津市中心妇产科医院普通妇科,300052

出　　处：《中国实用妇科与产科杂志》2004年第11期665-667,共3页Chinese Journal of Practical Gynecology and Obstetrics

摘　　要：目的　提高对子宫内膜间质肉瘤 (endometrialstromalsarcoma ,ESS)的诊断和处理水平。方法　回顾性分析 1 991～ 2 0 0 0年天津市中心妇产科医院 1 6例ESS的临床资料。以世界卫生组织 1 994年关于ESS的分类和国际抗癌协会 (UICC AJCCS)对子宫肉瘤的分期为标准 ,进行分类和分期。全部病例均经手术治疗。基本术式为全子宫双附件切除 ,术后辅助化疗和放疗。结果　 1 6例ESS中 ,高度恶性 2例 ,低度恶性 1 4例。前者预后差 ,因肿瘤转移死于术后 2 1个月内。后者预后较好 ,随访至 2 0 0 1～ 2 0 0 3年 ,存活 1 3例 ,5年存活率 91 7%。结论　ESS的恶性度与预后关系密切 ,应力争术前或术中确诊 ,作较广泛的切除 ,术后辅助放疗和化疗 ,以减少复发和提高存活率。Objective To improve the level of diagnosis and management of endometrial stromal sarcoma(ESS).Methods The medical data of the 16 cases with ESS which were treated in 1991～2000 in our hospital was analysed retrospectively.The classification and stage were divided according to the standard of ESS which was set by WHO in 1994 and sarcoma of uterus which was set by UICC-AJCCS.All patients were operated with the basic mode of total hysterectomy and bilateral appendectomy.Chemotherapy and radiotherapy were assisted after operations.Results There were 2 cases of high grade malignancy and 14 cases of low grade in 16 cases of ESS.The former two had a bad prognosis and died from metastasis of the tumor in 21 months after operation;the later had a better prognosis and there were 13 survivals and the survival rate of 5 years was 91 7% by the time 2001～2003.Conclusion The malignant degree of ESS is closely related to the prognosis.To reduce recurrent and increase survival rate we should strive to confirm the diagnosis before or during operation and perform wider resections and take radiotherapy and chemotherapy to assist.

关 键 词：子宫内膜间质肉瘤 全子宫双附件切除术 诊断 治疗 

分 类 号：R737.33[医药卫生—肿瘤]