A,C-Bridged Calix[6]arene: Relationship between the Length of Bridge and Conformation  

作　　者：龚淑玲 陈义坤 李俊 段和平 陈远荫 

机构地区：[1]College of Chemistry and Molecular Science, Wuhan University, Wuhan, Hubei 430072, China

出　　处：《Chinese Journal of Chemistry》2004年第6期573-576,共4页中国化学（英文版）

基　　金：Project supported by the National Natural Science Foundation of China (No. 20272044).

摘　　要：Three new A,C-diamide bridged p-tert-butylcalix[6]arenes were synthesized from p-tert-butylcalix[6]arenes by bridging ClCH2CONH(CH2)nNHCOCH2Cl (n=3, 4, 6) in acetonitrile using K2CO3 as a base in 17%—25% yields. It was found that the bridged calix[6]arenes with shorter bridges (n=2, 3, 4 in N',N'-bischloroacetodiamines) adopt cone conformation, but the last one (n=6) adopts alternate conformation, i.e., accompanying the lengthening of bridge, the conformation of A,C-bridged calix[6]arenes changes from cone to alternate.Three new A,C-diamide bridged p-tert-butylcalix[6]arenes were synthesized from p-tert-butylcalix[6]arenes by bridging ClCH2CONH(CH2)nNHCOCH2Cl (n=3, 4, 6) in acetonitrile using K2CO3 as a base in 17%—25% yields. It was found that the bridged calix[6]arenes with shorter bridges (n=2, 3, 4 in N',N'-bischloroacetodiamines) adopt cone conformation, but the last one (n=6) adopts alternate conformation, i.e., accompanying the lengthening of bridge, the conformation of A,C-bridged calix[6]arenes changes from cone to alternate.

关 键 词：CALIXARENE CALIX[6]ARENE CONFORMATION bridging diamide bridge 

分 类 号：O621[理学—有机化学]