黄艾美球虫侵犯宿主组织的超微研究  

THE STUDIES OF ENDOGENIC DEVELOTMENT AND ULTRASTRUCTURES AND HOST-PARASITE'S RELATIONSHIP OF EIMERIA FLAVESCENS

作　　者：王维[1] 林昆华[2] 殷佩云[2] 

机构地区：[1]甘肃农业大学兽医系 [2]北京农业大学兽医学院

出　　处：《中国兽医寄生虫病》1993年第4期15-19,共5页Chinese Journal of Veterinary Parasitology

摘　　要：利用透射电镜和扫描电镜相结合的技术对黄艾美球虫(E.flavescens)人工感染后的子孢子移动过程及被虫体寄生的宿主细胞形态学变化和粘膜形态学变化进行了观察。子孢子在进入小肠腺上皮过程中需白细胞介导,在白细胞内可发育成球形的滋养体,观察到有两个子孢子侵入同一白细胞的现象,但分别存在于各自的带虫空泡中。黄艾美球虫引起的肠粘膜损伤主要发生于感染177小时之后,其损伤主要表现在绒毛大片脱落,结缔组织裸露,表面可见到大量破损的孔洞及大量肠杆菌。被虫体寄生的腺上皮细胞基部膨胀,微绒毛脱落,细胞核膨大并部分包被虫体,有些细胞核裂解为二。The morphology of the caecum and colon mucosal surface and glandular epithelia of domestic rabbit infected with E, flavescens were studied with transmission and scanning electron micros- copes. The extensive mucosal surface and glandular epithelia damage were not observed until 177 hrs postinfection. The villi were destroyed, the large areas of caecum became denuded with bacteria invasion. Crypts parasited showed clear demaracation between the uninfected cells in the neck, the crypt bases tended to loose their microvili. In many cases, host cell nuclei were seen to partially envelopment the parasite leading to the binucleate appearance of some of the host cells. The sporozoites penetrated into the intestinal wall and were carried to the glandular epi- thelium by leukocytes.

关 键 词：黄艾美球虫 宿主组织 超微结构 透射电镜 扫描电镜 兔 致病机理 

分 类 号：S858.291[农业科学—临床兽医学] S852.723[农业科学—兽医学]