FNAC在甲状腺癌术前诊断中的应用价值  

Value of FNAC in preoperative diagnosis of thyroid carcinoma

作　　者：胡大学[1] 刘翔[1] 杨红[1] 肖广成[1] 

机构地区：[1]四川省人民医院病理科,成都610072

出　　处：《诊断病理学杂志》2003年第5期281-283,i008,共4页Chinese Journal of Diagnostic Pathology

基　　金：四川省卫生厅科研基金资助项目 (0 10 0 87)

摘　　要：目的　对FNAC在甲状腺癌术前诊断中的应用价值进行评价。方法　细针吸取组织细胞涂片 ,采用HE、Wright和免疫细胞化学染色诊断甲状腺癌 ,将术前FNAC结果与术后组织切片诊断进行对比分析。结果　术前FNAC诊断甲状腺癌 193例。术后有组织切片诊断对照 113例 ,两者完全符合和基本符合率为 87 6 % ,不符合为12 4 %。FNAC诊断甲状腺癌的敏感性为 91 7% ,阳性预测值为 98% ,假阳性为 2 7%。结论　术前FNAC诊断甲状腺癌敏感性高 ,应予推广。Objectives To evaluate the accuracy of fine needle aspiration cytology (FNAC) in the preoperative diagnosis of thyroid carcinoma. Methods FNAC smears were stained with H & E, Wright staining and immunocytochemistry and observed under light microscope. Results One hundred ninety-three cases of thyroid carcinoma were diagnosed by FNAC, in which 113 cases were confirmed by postoperative histological examination.The total conforming rate was 87.6%.The sensitivity of FNAC in diagnosing thyroid carcinoma was 91.7%.The positive prospective rate of FNAC of the thyroid carcinoma was 98%.Only 2.7% of these cases had a false-positive cytology. Conclusions The sensitivity of FNAC in preoperative diagnosing thyroid carcinoma is high. It is becoming a widely accepted and useful method in the preoperative assessment of palpable thyroid lesions.

关 键 词：术前诊断 甲状腺癌 FNAC 组织切片 应用价值 术后 免疫细胞化学染色 组织细胞 涂片 假阳性 

分 类 号：R736.1[医药卫生—肿瘤] R735[医药卫生—临床医学]