^(99)Tc^m-Tetrofosmin显像对乳腺癌及腋窝淋巴结转移诊断价值评价  

Evaluation of ^(99) Tc^m-Tetrofosmin Imaging in Detection of Primary Breast Cancer and Axillary Lymph Node Metastasis

作　　者：宋文忠[1] 周蕾蕾[2] 陈明曦[1] 谢红军[1] 黄劲[2] 刘锦平[2] 罗诚[2] 

机构地区：[1]四川省人民医院核医学科,四川成都610072 [2]四川省人民医院乳腺外科,四川成都610072

出　　处：《中国医学影像技术》2003年第11期1531-1533,共3页Chinese Journal of Medical Imaging Technology

基　　金：四川省卫生厅科研基金资助 (2 0 0 0 86)

摘　　要：目的　评价99Tcm Tetrofosmin乳腺显像对乳腺肿块及腋窝淋巴结性质的鉴别诊断价值。方法　采用前瞻性和盲法对 5 1例原发性乳腺癌和 43例乳腺良性肿块患者术前进行99Tcm Tetrofosmin乳腺和腋窝淋巴结平面显像 ,以病理结果为“金标准” ,评价该方法常规读片分析对病灶性质鉴别诊断的价值。结果　99Tcm Tetrofosmin乳腺平面显像对乳腺癌诊断的灵敏度为 88.2 % ,特异性为 88.4% ,准确率为 88.3 %。对乳腺癌淋巴结转移灶诊断分别为 5 3 .9% ,94.1%和 69.8%。结论　99Tcm Tetrofosmin乳腺显像作为一种非创性和简便的方法 ,对乳腺肿块及腋窝淋巴节性质的鉴别诊断有较大的价值 ,采用断层显像并结合其他诊断方法 ,能为临床提供更准确的诊断信息。Objective To evaluate the usefulness of 99 Tc m-Tetrofosmin imaging in detection of both primary breast cancer (PBC) and axillary lymph node metastasis (ALNM).Methods Fifty-one patients with PBC and 43 with breast benign masses were examined using SPECT planar imaging before operation.Conventional SPECT film was interpreted by more than 2 physicians with blind method.The imaging results were analyzed according to histopathological diagnoses.Results The sensitivity,specificity and accuracy of planar imaging were 88.2%,88.4% and 88.3% for the detection of PBC,respectively.The sensitivity was 53.9% for detecting ALNM.Specificity and accuracy were 94.1% and 69.8%,respectively.Conclusion 99 Tc m-Tetrofosmin imaging was useful tool in detection of both PBC and ALNM.It plays complementary role in the detection of breast cancer in some patients.

关 键 词：乳腺癌 体层摄影术 发射型计算机 单光子 放射性核素显像 

分 类 号：R737.9[医药卫生—肿瘤] R817.4[医药卫生—临床医学]