食管癌超分割与常规放疗前瞻性研究  

Prospective study on divided and routine radiotheraphy of esophageal carcinoma

作　　者：孟广典[1] 吴晓翠[1] 李秀平[1] 刘兴安 王跃伟[1] 李国文[2] 

机构地区：[1]河南省人民医院,郑州450003 [2]河南医科大学一附院,郑州450003

出　　处：《临床医学》1993年第3期101-103,共3页Clinical Medicine

摘　　要：1990年7月至12月,我们对收治的72例食管癌病人进行了超分割放疗与常规放疗的前瞻性随机临床研究。病人随机对照分组为常规放疗组(A 组)与超分割放疗组(B 组),两组病人临床情况基本相似。所有病例随访均超过一年。一年生存率分别为 A 组50%,B 组为77.8%,经统计学处理,B 组和 A 组 P<0.005,差异有显著意义。结果表明:超分割放射治疗食管癌作为一种新的治疗方法可提高食管癌的近期疗效及生存率。Form February 1990 to April 1991.72 patients with esophageal cancer were randomly divided into two groups:Group A—conventional fractionatiou(60～ 70Gy/30～35F,6～7wk);Group B—hyperfractionation am 1.4Gy,6…7hr.later,1.4Gy,to a total of(75～ 82Gy/67～72F,6～7wk),The conditions between the two groups were similar.The clinical results of treatment showed that:Not only immediate response of Group B was better than that of Group A,but also the one—year survival rate of Group B higher;The recent adverse reac- tion was similar in two groups.We believe that hyper- fractiouation could be adopted in the radiotherapy for esophageal carcinoma.

关 键 词：食管肿瘤 放射疗法 超分割 

分 类 号：R735.105[医药卫生—肿瘤]