直肠恶性癌样间质瘤误诊1例并文献复习  

Misdiagnostic Analysis of One Case of Rectal-Carcinoma-Like Gastrointestinal Stromal Tumor

作　　者：夏庆欣[1] 楚广民[1] 庄競[2] 乔思杰[1] 

机构地区：[1]河南省肿瘤医院病理科,河南郑州450008 [2]河南省肿瘤医院普外科,河南郑州450008

出　　处：《中国误诊学杂志》2004年第8期1173-1175,共3页Chinese Journal of Misdiagnostics

摘　　要：目的 :分析胃肠间质瘤 (GISTs)的误诊原因 ,探讨其组织学特点、诊断及鉴别诊断标准。方法 :采用 HE染色和免疫组织化学标记 ,报告直肠恶性癌样间质瘤 1例的误诊原因。结果 :临床表现为黑便、腹痛 ,肿瘤细胞呈梭形 ,部分区域呈上皮细胞样分化 ,两者之间有过渡。免疫组织化学 (IHC)为 :CKmix(- )、Vim(+)、 CD117(+)、Actin (- )、S- 10 0(- )及 CD34(- )。结论 :GISTs是胃肠道常见的间叶性肿瘤 ,组织起源有争议 ,其诊断及鉴别诊断主要依靠组织病理学和免疫组织化学。Objective:To analyse the reasons of misdiagnosis of gastrointestinal stromal tumors and to investigate the histopathological features and differential diagnosis.Methods:To report one case of rectal-carcinomia-like GISTs with H.E. print and immunohistochemistry.Results:Patient's clinical symptoms were melena and abdomional colic.Histopathologically,the tumor cells were spindle,and some tumor cells presented epithelial-like. Immunohistochemistry showed Ck(-),Vim(+),CD117(+),Actin(-),S-100(-),CD34(-).Conclusions:GISTs were usually non-eplthelial-tumor in gastrointestinal stromal. There was controversy on histological origin. The diagnosis and differentiatial diagnosis of GISTs mainly relied on histopathological and immunohistochemisical methods.

关 键 词：间质瘤 恶性 直肠 免疫组织化学 误诊原因 文献复习 GIST 结论 目的 过渡 

分 类 号：R735[医药卫生—肿瘤] R733[医药卫生—临床医学]