塑料电泳芯片微结构模压的试验研究  

EXPERIMENTAL RESEARCH OF HOT EMBOSSING OF MICROCHANNELS FOR PLASTIC CAPILLARY ELECTROPHORESIS CHIPS

作　　者：于建群[1] 王立鼎[2] 刘军山[2] 郭丽莎[2] 

机构地区：[1]吉林大学生物与农业工程学院,长春130025 [2]大连理工大学机械工程学院,大连116023

出　　处：《机械工程学报》2004年第11期93-97,共5页Journal of Mechanical Engineering

基　　金：中国博士后科学基金和吉林省科技发展计划资助项目(20020610)

摘　　要：塑料电泳芯片具有绝缘性、透光性好,材料价格便宜,成型容易,批量生产成本低等优点,是一种新型微型分析装置。研究塑料电泳芯片微通道模压的工艺过程和工艺参数,通过试验建立微通道尺寸与模板微凸起尺寸和模压工艺参数的关系,在此基础上提出了一种新的模压工艺,对于完善塑料电泳芯片结构设计和制作的基本理论和基本技术均有较大意义。A plastic capillary electrophoresis chip is a novel kind of miniaturized device for biochemistry analysis. The major advantages of the chip include high transmittance for light; low conductivity for electrokinetic pumping and electrophoretic separation; low cost for high volume production and disposal and easily manufacturing for high aspect ratio of microchannels on the chip. A process of hot embossing for plastic capillary electrophoresis chips is studied, the relationships among the dimensions of the microchannels, the dimensions of the raised image on the template and the process conditions of hot embossing, including temperature, pressure and time are established by experiment, based on these a novel process of hot embossing is proposed, which lays the foundation for basic theories and techniques of structural design and manufactures of the plastic chip.

关 键 词：电泳芯片 微流控芯片 生物芯片 微全分析系统 微机电系统 微细加工 微模压 

分 类 号：TN271[电子电信—物理电子学]