MR弥散加权成像在前列腺良恶性病变诊断中的价值初探  

MR diffusion-weighted imaging for differentiation of benign from malignant prostate lesions

作　　者：张继斌[1] 沈钧康[2] 许建铭[1] 李晓兵[1] 须同禄[1] 刘仁坚[1] 陆之安[2] 

机构地区：[1]苏州市第二人民医院放射科,江苏苏州215002 [2]苏州大学附属第二医院MRI室

出　　处：《中国医学影像技术》2004年第11期1732-1734,共3页Chinese Journal of Medical Imaging Technology

摘　　要：目的　探讨MR弥散加权成像 (DWI)表观弥散系数 (ADCs)在前列腺病变诊断中的价值。方法　对良性前列腺增生 (BPH) 42例、前列腺癌 (PCa) 15例进行MR弥散加权成像 ,测算病灶表观弥散系数 (ADCs)。结果　BPH组前列腺中央带增生结节与外周带的平均ADC值分别为 :( 1.783± 0 .2 82 )× 10 -3 mm2 /s和 ( 2 .0 2 5± 0 .3 5 8)× 10 -3 mm2 /s ;前列腺癌组前列腺中央带与外周带癌灶平均ADC值分别为 :( 1.63 2± 0 .0 82 )× 10 -3 mm2 /s和 ( 0 .2 67± 0 .0 7)× 10 -3 mm2 /s (P <0 .0 5 )。结论　DWI对于BPH、PCa可提供定量诊断信息 ,反映其病理变化 ;Objective To evaluate the value of diffusion weighted imaging (DWI) of apparent diffusion coefficients (ADCs) in distinguishing benign and malignant prostate lesions. Methods Forty-two cases with benign prostate hyperplasia (BPH) and 15 cases with prostate cancer (PCa) were examined by DWI. Results The ADCs of the central gland, peripheral zone of the BPH groups was (1.783±0.282)×10^(-3) mm^2/s, (2.025±0.358)×10^(-3) mm^2/s, respectively, and (1.632±0.082)×10^(-3) mm^2/s, (0.267±0.07)×10^(-3) mm^2/s in the prostate cancer groups, respectively. The average ADCs of peripheral zone in the prostate cancer were significantly lower than that of the BPH (P<0.05). Conclusion DWI can give quantitative information for pathological changes in BPH and PCa. ADCs are effective parameters in distinguishing malignant and benign prostate lesions. [

关 键 词：前列腺增生 前列腺癌 磁共振成像 弥散 

分 类 号：R737.25[医药卫生—肿瘤] R445.2[医药卫生—临床医学]