75例肾脏占位病变患者肾小球滤过率和血压分析  

An Analysis of Glomerular Filtration Rate (GFR) and Hypertensionin 75 Cases with Renal Space-occupying Lesion

作　　者：赵铭[1] 张承刚[2] 张红雨 田保国[1] 王丽丽[1] 吴波[1] 

机构地区：[1]山西省肿瘤医院,山西太原030013 [2]山西医科大学第一医院,山西太原030001

出　　处：《肿瘤学杂志》2004年第6期434-435,共2页Journal of Chinese Oncology

摘　　要：[目的]探讨肾脏占位病变引起高血压的危险因素。[方法]75例肾脏占位病变患者,术前两天进行99mTc鄄DTPA肾脏动态显像,计算双肾肾小球滤过率(GFR),并记录血压。依据病理结果,将患者分为肾细胞癌组和非肾细胞癌组,分别计算两组高血压的发生率。依据健侧肾脏GFR≥或<50ml/min,将患者分为两组,比较两组高血压的发生率。[结果]肾细胞癌组高血压的发生率为17.4%,而非肾细胞癌组为20.7%,两组比较无显著性差异。在GFR≥50ml/min组中未发现高血压患者,GFR<50ml/min组中高血压患者14例,占25%,两组之间存在显著性差异(P<0.05)。[结论]GATES法健肾GFR<50ml/min是肾脏占位病变合并高血压的危险因素。To explore the risk factors caused by renal space-occupying lesion. Seventy-five cases with renal space-occupying lesion underwent radical nephrectomy were studied. 99mTc-DTPA dynamic renography was performed in all patients 2 days before operation. Pre-operative glomerular filtration rate(GATES) and blood pressure were measured. These patients were divided into renal cell carcinoma group and non renalcell carcinoma group,based on post-operative pathologic study. The incidence rates of hypertension between two groups were compared. All cases were divided into two groups: lesion GFR≥50ml/min group and GFR<50ml/min group. The incidence rates were 17.4% in hypertension of renal cell carcinoma group and 20.7% in non renal cell carcinoma group. There was no significant difference between two groups. There was no hypertension case in the GFR≥50ml/min group. Fourteen hypertension cases were founded in GFR<50ml/min group. The incidence rate of hypertension in GFR<50ml/min group was 25%. There was a significant difference between two groups(P<0.05). [Conclusion] GFR<50ml/min in the contralateral kindey without space-occupying lesion is the risk factor of hypertension in patients with space-occupying lesion.

关 键 词：肾脏占位 高血压 动态显像 

分 类 号：R730.44[医药卫生—肿瘤]