食管癌组织MRP1/CD9的表达及临床意义  

The Expression and Clinical Significance of Motility-related Protein(MRP1/CD9)in Esophageal Cancer

作　　者：季润元[1] 沈阳[2] 王成海[3] 孙泽[4] 冯振卿[5] 

机构地区：[1]江苏省淮阴卫生学校,江苏淮安223300 [2]江苏省淮安市第二人民医院,江苏淮安223302 [3]扬州大学医学院,江苏扬州225001 [4]江苏省泗洪县分金亭医院,江苏泗洪223600 [5]南京医科大学病理学系,江苏南京210029

出　　处：《中国肿瘤》2004年第12期812-813,共2页China Cancer

摘　　要：[目的]探讨食管癌组织中MRP1/CD9表达的临床意义。[方法]应用免疫组化SABC法,检测54例食管癌组织中MRP1/CD9的表达。[结果]无淋巴结转移的食管癌组织和有淋巴结转移的食管癌组织MRP1/CD9阳性表达率分别为68.4%(26/38)、31.3%(5/16)。食管癌组织MRP1/CD9的表达与淋巴结转移、肿瘤的分级、术后存活时间显著相关(P<0.05)。[结论]MRP1/CD9可作为食管癌的预后指标。To investigate the expression of motility-related protein 1(MRP1/CD9) in esophageal cancer tissues and its clinical significance.The expression of MRP1/CD9 in esophageal cancer tissues was assayed by SABC immunohistochemical method in 54 cases.The expression of MRP-1/CD9 in esophageal cancer tissue in patient without and with lymph node metastasis was 68.4%(26/38)and 31.3%(5/16)respectively.The expression of MRP-1/CD9 correlated with lymph node metastasis,tumor differentiation,and postoperative survival(P<0.05).[Conclusion]MRP1/CD9 is a prognostic index for esophageal cancer.

关 键 词：MRP1/CD9 食管肿瘤 免疫组织化学 

分 类 号：R735.1[医药卫生—肿瘤] R73-3[医药卫生—临床医学]