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作 者:张勇进[1] 王文吉[1] 黎蕾[1] 沈颖[1] 高巧云[1]
机构地区:[1]复旦大学附属眼耳鼻喉科医院,上海200031
出 处:《中华眼底病杂志》2004年第6期335-338,共4页Chinese Journal of Ocular Fundus Diseases
摘 要:目的 探讨多灶性脉络膜炎 (MFC)患者的临床及荧光素眼底血管造影 (FFA)表现的特征。 方法 经临床及 FFA确诊为 MFC患者 8例 ,分析总结其临床及 FFA的表现。 结果 8例患者均为双眼高度近视 (- 6 .0 0~ - 8.0 0 D) ,年龄 16~ 32岁 ,7例为女性 ,1例为男性。 8例患者双侧眼底后极部均有散在黄白色点状病灶 ,其中 6例还伴有黄斑部脉络膜新生血管膜 (CNV) (双眼 2例 ,单眼 4例 )。 8例患者眼底病灶都较多 ,严重程度相近 ,玻璃体内有少量炎性细胞 ;7例 FFA早期眼底黄白色病灶为弱荧光 ,后期染色 ;伴有 CNV病灶周围有出血者 ,FFA显示有相应表现。 结论 MFC多发生于近视患者 ,年轻女性多见 ,多双眼发病 ,眼底表现为以后极部为主的多个黄白色斑点 ,FFA早期活动性病灶表现为弱荧光 ,后期染色。可伴发Objective To observe the clinical manifestations and fe at ures of fundus fluorescein angiograms (FFA) of patients with multifocal choroidi tis (MFC). Methods The data of 8 patients who had been diagnos ed by clinic and FFA as with MFC were collected, and their clinical manifestatio ns and results of FFA were analyzed and valued. Results The ag e of the 7 female and 1 male patients ranged from 16 to 32, and all of the 8 pa tients had high myopia (from -6.00 D to -8.00 D) with binocular multiple small yellowish white lesions in posterior pole of the fundus and a few phlogistic ce lls in vitreous body. In addition, macular choroidal neovascularization membrane (CNV) was found in 6 patients, binocular in 2 and monocular in 4. The results o f FFA in 7 patients showed hypofluorescence of the yellowish-white lesions at t he early phase and pigmentation at the late phase; Corresponding manifestations of FFA could be found in the patients attended by CNV surrounded by leakage. Conclusion MFC are mostly diagnosed in young females with myopia. Most of the patients had binocular affection with multiple small yellowish whit e lesions at the posterior pole, whose FFA shows hypofluoresence of the active l esions at the early phase and pigmentation at the late phase. CNV may occur in p atients with MFC.
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