20例腮腺原发性恶性淋巴瘤的临床病理和免疫组化的研究  

Primary non-Hodgkin's lymphoma on parotid gland clinicopathologic and immunohistochemical study

作　　者：夏伟亚[1] 李采[1] 刘瑷如[1] 

机构地区：[1]上海第二医科大学口腔医学院口腔病理教研室,上海第二医种大学超声病理室

出　　处：《上海口腔医学》1994年第3期139-141,共3页Shanghai Journal of Stomatology

摘　　要：对２０例腮腺原发性恶性淋巴瘤，作了临床病理和免疫组化的研究，结果Ｂ细胞来源９例（４５％），Ｔ细胞来源８例（４０％），小淋巴细胞性３例（１５％），１１例作了免疫组化，除１例原病理诊断为淋巴浆细胞性而免疫表型为Ｔ细胞外．余１０例前后诊断相符，２０例随访获得随访结果的１６例中，３例在一年内死于肿瘤，其中Ｂ裂细胞性、淋巴母细胞性及多形Ｔ细胞性各１例；目前仍存活的１３例，存活了１５个月至９年３个月，其中低度恶性２例（均为小淋巴细胞性），中度恶性７例（Ｂ裂细胞性５例，Ｂ混合细胞性２例），高度恶性４例（透明细胞性２例，多形Ｔ细胞住２例）．均经手术加中西医综合治疗，预后良好。A clinico-pathologic and immunohistochemical study of 20 cases of primary nonHodgkin's lymphoma on the parotid gland was made.The result showed 45% of the cases originated from B cells,white 40% from T cells,the rest 15% from the small lymphocytes.Immunohistochemical study was made on 11 cases,the result of immunophenotype was in concordance with the histopathologic diagnosis in 10 cases,except in one case which was initially diagnosed as plasmocytoid lymphocytic lymphoma,but the immunophenotype suggested that it was Tcell type of malignant lymphoma(ML).Follow-up data can be collceted in 16 cases(80%).Three of the 16 cases(18.75%)died of the tumor within one year,they were diagnosed initially as B cleaved cell,lymphoplastic cell and polymorphic T cell type of ML,each in 1 case.Other cases survived from 15 months to 9.25 years,among them 2 were diagnosed as low-grade ML(both of small lymphocyte type),7 cases as middle-grade ML(5 of B cleaved cell,2 of B mixed type),and 4 cases as high-grade ML(2 of clear T cell,2 of polymorphic T cell type).They were treated by surgical removal and combined western and traditional Chinese medicine,their prognosis was quite good.

关 键 词：腮腺原发性恶性淋巴瘤 病理 免疫组化 T细胞 

分 类 号：R739.87[医药卫生—肿瘤]