胃印戒细胞癌粘蛋白成分与生物学行为的关系  

THE RELATIONSHIP BETWEEN MUCIN AND BIOLOGICAL BEHAVIOUR IN SIGNET-RING CELL CARCINOMA

作　　者：黄玫[1] 王广钧[1] 

机构地区：[1]内蒙古医学院病理解剖学教研室

出　　处：《内蒙古医学院学报》1993年第1期13-17,共5页Acta Academiae Medicinae Neimongol

摘　　要：用组织化学及免疫组织化学方法对55例胃印戒细胞癌粘蛋白成分进行检测和分析。结果表明不同形态印戒细胞同源于一个细胞前体,即起源于胃腺颈部细胞。在观察以不同类型细胞为主的印戎细胞癌与预后的关系时发现,A型或B型患者5年生存率较C型患者为低(P<0.05)。不同类型的癌细胞有不同的凝集素标记,其中PNA主要表达于B型癌细胞;PHA主要表达于C型癌细胞。对印戒细胞癌的进一步分型有一定帮助,有利于对患者的预后做出初步的判断,对临床有指导意义。In this paper, histochemical and immunohistochemical methods were used to detect mucin in order to confirm the relation between different types of SRCC and their prognosis and to study their histogenesis. It was found that the patients of mainly type A and type B have a low survive rate compared with that of mainly type C(P<0.05). The result showed that different lcctin receptors were detected in different types of cancer cells, and the relationship presented between types of SRCC and the prognosis, All of the facts may be confirmed to help in further classification of SRCC.

关 键 词：印戒细胞癌 粘蛋白 胃肿瘤 

分 类 号：R735.202[医药卫生—肿瘤]