可交联聚磷酸酯组织工程材料的合成  

Synthesis of Crosslinkable Unsaturated Polyphosphoester for Tissue Engineering

作　　者：刘承美[1] 邱进俊[1] 陈明君[2] 

机构地区：[1]华中科技大学化学系 [2]三峡学院化学工程系,重庆万县634000

出　　处：《湖北民族学院学报（自然科学版）》2004年第4期5-8,共4页Journal of Hubei Minzu University(Natural Science Edition)

基　　金：国家自然科学基金资助项目(20374022).

摘　　要：以富马酸和三氯氧磷为起始原料,合成了主链重复结构单元中含不饱和双键的聚磷酸酯.研究了合成条件对聚合反应的影响,并对其进行了FTIR及NMR表征.GPC研究结果表明随反应时间延长,聚合度增大,聚合物分子量趋于增大但分散性减小.Unsaturated polyphosphoester(UPPE) containing unsaturated double bonds in main chain was synthesized with fumaric acid,1,2-propylene glycol and phosphorous oxychloride as the initiation materials. The effects of reaction condition on polymerization were studied and the structure of final polymer characterized by FTIR and NMR. The GPC results indicated that the polymerization degree increased with the extension of reaction tine and the molecular weight distribution was tend to be monodispersity.

关 键 词：组织工程材料 生物高分子 可降解材料 不饱和聚磷酸酯 富马酸二(1 2-丙二醇)酯 

分 类 号：O631.5[理学—高分子化学]