无龋儿童和患龋儿童唾液中免疫成分的比较  

Comparison of saliva immune ingredient of cary and non-cary children

作　　者：吴慧华[1] 王燕秋[1] 

机构地区：[1]华中科技大学同济医学院附属同济医院口腔医学中心,湖北武汉430030

出　　处：《临床口腔医学杂志》2004年第12期753-754,共2页Journal of Clinical Stomatology

摘　　要：目的 :对无龋儿童和患龋儿童唾液中免疫成分进行检测 ,研究龋病与唾液中免疫成分的关系。方法 :对 2 0 4名 4～ 6岁幼儿园儿童进行口腔检查 ,收集混合唾液测定 pH值、SIgA和溶菌酶的含量 ,并对无龋儿童和患龋儿童唾液免疫成分进行比较。结果 :2 0 4名儿童中 ,无龋 5 9名。患龋 14 5名 ,患龋率 71.0 8%。患龋儿童龋均5 .2 6,受检儿童龋均 3 .74。患龋者唾液 pH 7.0 4± 0 .3 7,无龋者唾液 pH 7.14± 0 .3 9,两组比较无显著性差异 (P >0 .0 5 )。患龋者唾液SIgA为 5 8.81± 40 .76μg/ml ,无龋者SIgA为 48.61± 2 5 .83 μg/ml,两者比较具有显著性差异(P <0 .0 5 )。患龋者唾液溶菌酶含量 18.63± 2 0 .64 μg/ml ,无龋者溶菌酶含量 13 .77± 12 .2 5 μg/ml ,两者比较具有显著性差异 (P <0 .0 5 )。结论 :无龋儿童与患龋儿童唾液 pH值无明显差异 ,患龋儿童SIgA及溶菌酶含量较无龋儿童低 ,SIgA及溶菌酶在龋病发病中起重要作用。Objective:To investigate the interrelationship between dental cary and saliva immune ingredient through measuring saliva immune ingredient in cary and non-cary children.Method:Oral examinations were performed in 204 kindergarden children of 4～6 years old pH , SIgA and lysozyme contents of general saliva were measured and compared between cary and non-cary children.Result:There were 59 non-cary cases (28.92%) and 145 cary children ( 71.08% ) in 204 children. Number of caried teeth was averaged at 5.26 in cary children . Number of caried teeth was averaged at 3.74 among 204 children . Saliva pH of cary children and non-cary children were 7.04±0.37 and 7.14±0.39, respectively , showing no significant difference (P>0.05). Saliva SIgA of cary children (58.81±40.76 ug/ml) increased significantly (P<0.05) compared with that non-cary children (48.61±25.83 ug/ml). Saliva lysozyme content of cary children (18.63±20.64 ug/ml) increased significantly (P<0.05) compared with that of non-cary children ( 13.77±12.25 ug/ml) , likewisely .Conclusion:Saliva pH has no significant difference between cary incidence and number of caried teeth . SIgA and lysozyme contents of cary children is higher than that of non-cary children . SIgA and lysozyme play important role in dental cary pathogenesis .

关 键 词：龋齿 唾液 pH SIGA 溶菌酶 

分 类 号：R781.1[医药卫生—口腔医学]