影响肝外胆管癌手术切除的因素分析  

Analysis of Factors Impacting Bile Duct Carcinoma Resection

作　　者：崔平[1] 段体德[1] 戴书鹏[1] 胡筑培[1] 

机构地区：[1]昆明医学院第一附属医院肝胆外科,昆明650032

出　　处：《昆明医学院学报》2004年第4期70-72,共3页Journal of Kunming Medical College

摘　　要：目的 :探讨影响肝外胆管癌手术切除的主要因素 ,进一步对该肿瘤外科手术难度和风险加深认识 .方法 :对确诊肝外胆管癌 95例中的 85例手术病例 ,其中 36例行肿瘤切除 ,选择性别、年龄、肿瘤部位、肿瘤病理类型、形态类型、肿瘤大小、周围血管及神经浸润、肝脏及淋巴转移 9个影响因素 ,进行切除组与非切除组单因素对照分析 .结果 :全组手术率 89 4 7% ,切除 36例 (37 89% ) ,单因素分析显示影响胆管癌切除的显著性因素有肿瘤组织学、管壁浸润深度、外周浸润、转移、肿瘤形态大小和肿瘤部位 (P <0 0 5 ) ,而性别、年龄因素对肿瘤切除影响是非显著的 (P >0 0 5 ) .结论 :胆管癌因其有浸润性生长的生物学特性 ,造成切除率低的现实 ,手术难度和风险极高 ,只有早期诊断技术和手术技术的进步 ,才有望提高切除率 .Objective: To study the factors impacting bile duct carcinoma resection and to identify the risk of operation. Methods: In 95 patients with extrahepatic bile duct carcinoma in hospital from 1992 to 2003, 85 patients were treated by surgery, 36 patients actualized resection. 9 possible factors such as sex, age, histological types, tumour position, sharp, size, pancreatic and duodenal invasion, liver and lymph node metastasis were analyzed. The results showed that histological types, tumor position, sharp, pancreatic and duodenal invasion were significant factors (P<0.05); the others were secondary (P>0.05). Conclusion: Tumor cells of bile duct have high invasion characteristics which brings risk and difficulty of resection. No other than improved technology of operation and early diagnosis can enhance resection rate.

关 键 词：肝外胆管癌 手术切除 切除率 手术难度 肿瘤切除 肿瘤部位 影响 形态类型 确诊 性别 

分 类 号：R735[医药卫生—肿瘤] R657[医药卫生—临床医学]