功能高分子在新型给药系统中的应用  

A Review of the Application of Smart Polymer in New Drug Delivery Systems

作　　者：丁富新[1] 江田民[1] 昝佳[1] 蒋国强[1] 谭丰苹[1] 

机构地区：[1]清华大学化学工程系,北京100084

出　　处：《精细化工》2004年第12期923-926,937,共5页Fine Chemicals

基　　金：国家自然科学基金(20376038);教育部博士点专项基金(20020003056)

摘　　要：功能高分子材料具有独特的物理和化学性能,近年来在各类给药系统中有着广泛的应用。该文对功能高分子在新型给药系统中的应用及研究进展进行了评述;结合具体药物剂型,针对不同给药系统的特点和实际需要以及功能高分子的相关特性,讨论了功能高分子材料在药物控缓释中的独特作用和在不同给药系统中的应用前景。The new drug delivery systems should keep the drug at a desired therapeutic level in the body while avoiding the need for frequent administration. With the rapid development of drug delivery systems,more and more smart polymers with unique characteristics have been synthesized and used as the key materials in these systems,and the integrants of the polymer play important role in controlled drug release processes.A review of the application of smart polymers in drug delivery systems is given in this article,with the emphasis on the function and role of smart polymers in drug release processes.The progress and further applications of smart polymers in this area are discussed.

关 键 词：功能高分子 药物控缓释 渗透泵 定位 微囊化 植人 

分 类 号：R97[医药卫生—药品]