Novel Role of Carbon Dioxide as a Selective Agent in Palladium-Catalyzed Cyclotrimerization of Alkynes  

作　　者：李金恒 谢叶香 

机构地区：[1]Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research, College of Chemistry and Chemi-cal Engineering, Hunan Normal University, Changsha, Hunan 410081, China

出　　处：《Chinese Journal of Chemistry》2004年第12期1421-1424,共4页中国化学（英文版）

基　　金：Project supported by the National Natural Science Foundation of China (No. 20202002); Hunan Province Education Department (No. 02C211); and Hunan Normal University (2001).

摘　　要：Carbon dioxide was found as a selective agent to promote the palladium-catalyzed cyclotrimerization of alkynes in water. Both aryl and alkylacetylenes afforded the corresponding cyclotrimerization products regioselectively in high yields using PdCl2, CuCl2, and CO2 as the catalytic system. However, tert-butylacetylene bearing a bulky group gave a dimerization product. Mechanism of this reaction was also discussed.Carbon dioxide was found as a selective agent to promote the palladium-catalyzed cyclotrimerization of alkynes in water. Both aryl and alkylacetylenes afforded the corresponding cyclotrimerization products regioselectively in high yields using PdCl2, CuCl2, and CO2 as the catalytic system. However, tert-butylacetylene bearing a bulky group gave a dimerization product. Mechanism of this reaction was also discussed.

关 键 词：carbon dioxide a selective agent palladium CYCLOTRIMERIZATION ALKYNE 

分 类 号：O643.3[理学—物理化学]