凯西莱治疗酒精性脂肪肝40例临床分析  

Clinical investigation on treatment of alcoholic fatty liver with Tiopronin

作　　者：黄厚章[1] 杨珂珂[2] 曹俊[3] 

机构地区：[1]安徽省滁州市第一人民医院内科,239000 [2]蚌埠医学院附属医院内科 [3]天长市人民医院内科

出　　处：《实用全科医学》2005年第1期12-13,共2页Applied Journal Of General Practice

摘　　要：目的　观察注射用凯西莱治疗酒精性脂肪肝的临床疗效。方法　采用凯西莱治疗酒精性脂肪肝 40例 ,与甘利欣治疗 3 7例随机对照。结果　凯西莱治疗 3个月可明显改善患者临床症状 ,治疗组SGPT、SGOT、TC(血浆总三酰甘油 )、TG(血浆总胆固醇 )、A G(白蛋白 球蛋白 )复常率分别为 95 .0 %、90 .0 % 88.6%、88.9%、75 .8% ,与对照组比较差异有显著性 (P <0 .0 1)。结论　凯西莱可有效改善酒精性脂肪肝患者的临床症状 ,肝功能 ,降低血脂 ,提高整体治疗酒精性脂肪肝的疗效。Objective To study the curative effect of T iopronin on alcoholic fatty liver.Methods 40 patients with alcoholic fatty liver w ere treated with T iopronin and 37 patients with alcoholic fatty liver were treated with diammonium glycyrrhizinate as controls.Results Tiopronin could remarka bly ameliorate pat ients' clinical symptoms after 3 months of treatment. In treatment group, recove ry ratios of SGPT, SGOT, TC, TG were 95%?90%?88.6%?88.9% respectively. The di fference between two groups was significant (P<0.01). Conclusions Tiopronin co uld ameliorate the clinical symptoms of patients with alcoholic fatty liver, imp rove the liver function and decrease plasma triglyceride of patients. So it is h elpful to patients with alcoholic fatty liver.

关 键 词：整体治疗 酒精性脂肪肝 注射用凯西莱 患者 血浆 对照组 降低血脂 治疗组 三酰甘油 总胆固醇 

分 类 号：R575[医药卫生—消化系统] R735.7[医药卫生—内科学]