毫米波、槲皮素对培养人舌鳞癌细胞贴壁率影响的研究  

The analysis of effect of millimeter wave and quercetin on the attachment efficiency of squamous cell carcinomas of human tongue in vitro

作　　者：黄玉云[1] 尹丰圣[1] 李秉琦[2] 张富鑫[3] 

机构地区：[1]南通医学院附属医院口腔科,江苏南通226000 [2]华西医科大学口腔医学院 [3]成都电子科技大学

出　　处：《临床口腔医学杂志》2005年第1期26-27,共2页Journal of Clinical Stomatology

摘　　要：目的 :观察毫米波 (mmW )对培养人舌鳞癌细胞贴壁率的影响。方法 :对人舌鳞癌细胞用频率为 3 6.9GHz、功率密度为 10mW /cm2 的毫米波进行照射 ,观察对其影响 ,并以细胞计数法测定细胞贴壁率的变化。同时以抗癌剂槲皮素 (Quercetin ,QUE)为阳性对照 ,观察联合应用有无协同效应。结果 :Tca8113细胞经mmW 10 .0mW /cm2 连续作用 5d后消化传代 ,细胞贴壁率与对照组相比有明显减少 ,差异有统计学意义 (P <0 .0 1) ;和槲皮素联合应用有协同效应。结论 :毫米波辐射能降低舌癌细胞的贴壁率 ,有可能阻断癌细胞的转移和浸润。Objective:To observe the change of millmeter Wave (mmW) on the attachment efficiency of squamous cell carcinomas of human tongue in vitro. Method:The effects of mmW (36.9 GHz、10 mW/cm 2) on the attachment efficiency of the human squamous cell line were evaluated by the methods of cell counting .And observe cooperate effective with anticancer Quercetin (QUE) with the positive control group.Result:When a five-day treatment .Tca8113 cells attachment efficiency decreased significantly compared with the control group, the discrepancy is significant(P<0.01);there are cooprate effective whten mmW works in coordination with quercetin.Conclusion: mmW can reduce the attachment efficiency of the human squamous cell,mmW may be prevented transfer and invade of the human squamous cell.

关 键 词：肿瘤 舌鳞癌 毫米波 槲皮素 

分 类 号：R730.21[医药卫生—肿瘤]