肥大细胞在甲基胆蒽诱发的小鼠宫颈鳞癌间质中的分布  

The Distribution of Mast Cells in the Squamous Cell Carcinoma of Mouse Cervix Induced by 20-Methylcholanthrene

作　　者：景雅[1] 彭希平[1] 薛润梅[1] 乔从进[1] 姜树山[2] 安小敏[3] 

机构地区：[1]山西医学院组胚教研室 [2]山西医学院法医病理学教研室 [3]山西医学院中心仪器室

出　　处：《山西医学院学报》1993年第2期106-108,250-251,共3页

摘　　要：本文用甲苯胺蓝染色法对甲基胆蒽诱发的小鼠宫颈鳞癌间质中肥大细胞的分布进行了观察。结果表明,肥大细胞主要分布在癌旁间质和深层间质。癌间质中数量少(P<0.05),颗粒稀疏,并有明显脱颗粒现象。我们认为,癌间质中肥大细胞数量少是由于肥大细胞脱颗粒的结果,是肥大细胞功能状态的一种形态学表现,并非肥大细胞数量的真正减少。The distribution of mast cells in the squamous cell carcinoma of the mouse cervix induced by 20-methylcholanthrene was investigated after staining with toluidine blue. The results showed that the number of mast cells in the stroma around the tumor and in the deep stroma was significantly greater than that found within the tumor (P<0.05). The mast cells within the tumor were lessgranulated and obvious degranulation was observed. Therefore, we consider that the decrease of mast cells within the tumor may be looked upon as a morphologic expression of mast cell functional status rather than a real decrease of mast cell in number.

关 键 词：小鼠 子宫肿瘤 肥大细胞 

分 类 号：R737.33[医药卫生—肿瘤]