中西医结合治疗重症急性胰腺炎的临床研究  

Clinical study on treatment of severe acute pancreatitis by traditional Chinese medicine combined with Western medicine

作　　者：刘俊[1] 范崇九[1] 殷杰[1] 张德进[1] 吕振冠[1] 谢孝东[1] 陈玉泉[2] 沈洪薰[2] 朱良春[3] 

机构地区：[1]南通医学院附属海安医院,江苏南通226600 [2]南通医学院附属医院,江苏南通226001 [3]南通市中医院,江苏南通226001

出　　处：《肝胆胰外科杂志》2004年第4期269-270,共2页Journal of Hepatopancreatobiliary Surgery

基　　金：江苏省卫生厅中医药管理局资助课题 ( 95 5 1号 )

摘　　要：目的 :探讨重症急性胰腺炎 (SAP)采用中西医结合方法治疗的临床意义。方法 :我院外科 1995年6月至 2 0 0 3年 6月间收治SAP 136例 ,随机分成研究组和对照组各 6 8例 ,对照组早期采用传统的方法治疗 ,研究组在传统治疗方法的基础上应用通腑攻下方点滴法保留灌肠 ,对比分析两组的并发症发生率、中转手术率和病死率。结果 :①研究组并发症发生率 ( 4 2 .6 % )比对照组 ( 6 0 .3% )明显降低 (P <0 .0 5 )。②研究组早期胰外脏器损害的发生率 ( 2 6 .5 % ) ,也比对照组 ( 4 8.5 % )显著降低 (P <0 .0 1)。③中转手术率研究组 ( 13.2 % )比对照组 ( 2 3.5 % )相对降低 ,但无显著差异 (P >0 .0 5 )。④病死率研究组 ( 11.6 % )亦较对照组 ( 2 5 .0 % )显著降低 (P <0 .0 5 )。结论 :SAP早期应用中西医结合方法治疗有明显作用 ,其病死率为 11.6 % ,比对照组明显降低 ,可作为SAP的综合治疗的重要部分 。Objective:To investigate the curative effect of traditional Chinese medicine combined with Western medicine for severe acute pancreatitis(SAP).Methods:136 cases of SAP were randomized into two groups. Group A(n=68) were treated by traditional Chinese medicine combined with Western medicine,Group B(n=68) were treated in early stage with traditional Chinese medicine method. The rate of conversion of no-operation to operation,morbidity and mortality were compared between group A and B.Results:①The morbidity was significantly decreased in group A(42.6%),compared with group B(60.3%)(P<0.05).②The incidence of functional disorder of extrapancreatic organ was significantly decreased in group A,too (26.5%)(P<0.01).③The rate of conversion of no-operation to operation was relatively decreased(13.2%)(P>0.05).④The mortality was significantly decreased in group A(11.6%)(P<0.05).Conclusion:The way of traditional Chinese medicine combined with Western Medicine is a new option for the treatment of early stage SAP. It is important part of comprehensive treatment for SAP,and is of good applied prospects for treatment of SAP.

关 键 词：重症急性胰腺炎 中西医结合疗法 大黄 中药 保留灌肠 并发症 治愈率 

分 类 号：R576[医药卫生—消化系统]