骨髓未成熟网织红细胞指数在白血病化疗中的临床意义  

The clinical significance of bone marrow immature reticulocyte fraction in monitoring the recovery of bone marrow function after chemotherapy

作　　者：蹇启政[1] 施阳[1] 陈梅[1] 祝彪[1] 

机构地区：[1]四川省人民医院,成都610072

出　　处：《重庆医学》2005年第1期98-98,100,共2页Chongqing medicine

摘　　要：目的　探讨采用骨髓未成熟网织红细胞指数 (IRF)监测急性白血病患者化疗前、后骨髓功能的临床价值。方法　采用CELL DYN370 0型血液细胞分析仪检测骨髓及血中不同天数未成熟网织红细胞指数 (IRF)、网织红细胞比率 (Ret)。结果　白血病化疗组 :IRF在骨髓 10d开始升高 ,2 5d达高峰 ,Ret 15d开始升高 ,30d达高峰 ,且粒红巨三系增生活跃 ,而血中IRF ,15d才开始升高 ,2 5d相当于骨髓 2 0d的水平。结论　IRF无论在骨髓及血中均早于Ret升高 ,而骨髓IRF早于血中 5d升高。说明骨髓IRF检测在快速判断白血病化疗疗效方面具有重要的应用价值。Objective To investigate the clinical significance of bone marrow reticulocyte(Ret)and immature reticulocyte fraction(IRF)in monitoring the recovery of bone marrow function after leukemia chemotherapy.Methods IRF,Ret were detected by CELL-DYN 3700 Automated Hematology Analyzer in different days.Results In chemotherapy group:IRF began to increase at 10(15)d,and to go its top at 25d in bone marrow(blood).Conclusions IRF began to increase 5d earlier in bone marrow than in blood.It is of significance in judging curative effect of the leukemia chemotherapy.

关 键 词：白血病 化学疗法 网织红细胞指数 

分 类 号：R733.7[医药卫生—肿瘤] R730.53[医药卫生—临床医学]