^(18)F-FDG-SPECT/CT显像在肺癌诊断的临床应用  

^(18)F-FDG- SPECT/CT Imaging in Diagnosis of Patients with Lung Cancer

作　　者：郑健[1] 阮征[1] 黄海龙[1] 张闻瑞[2] 赵晋华[2] 

机构地区：[1]上海市第一人民医院胸外科,上海200085 [2]上海市第一人民医院核医学科,上海200085

出　　处：《中国临床医学》2004年第6期992-994,共3页Chinese Journal of Clinical Medicine

摘　　要：目的 :研究18F -FDG双探头符合线路SPECT/CT在肺癌诊断和鉴别诊断中的临床应用价值。方法 :对 6 1例肺部肿块患者进行18F -FDG -SPECT/CT检查 ,对良恶性肿块的摄取比值进行比较。并将CT检查和肺癌手术病理进行对照。结果 :以摄取比值R≥ 2为标准 ,18F -FDG -SPECT/CT对肺癌诊断的敏感性是 83% ,特异性是 86 % ,准确率是 81%。对纵隔淋巴结转移的诊断和病理结果的符合率分别是 88% ,与CT诊断两者有显著性差异。结论 :18F -FDG -SPECT /CT对肺癌的诊断 ,良恶性肿瘤的鉴别 ,以及临床分期有重要的应用价值。Objective: To evaluate the clinical value of 18F-FDG dual-head coincidence SPECT/CT in diagnosis of non -small cell l ung cancer.Methods:Sixty-one patients with lung mass underwent 18F-FD G dual-head coincidence SPECT/CT imageing and chest enhanced CT imageing before surery and compared for analysis of histological examination of lung mass. Results: IF R≥2, it can be postive. The sensitivity, specif icity and accuracy in differentiating malignant and benignant lesions of 18 F-FDG- SPECT/CT were 84%, 86%,81%, respectively. The histological examination of lympho nodes sampled from surgery was used as the standard for mediastinal, 18F-FDG- SPECT/CT is superior to morphological imaging by CT. Conclusion:Combined functional -anatonical image of 18F-FD G-SPECT/CT has potential to improve stag and localization procedure before surge ry.It is an excellent modality in diagnosis and differential diagnosis of lung c ancer.

关 键 词：诊断 ^18F-FDG SPECT 肺癌 临床应用 CT检查 摄取 目的 显著性差异 标准 

分 类 号：R734.2[医药卫生—肿瘤] R737[医药卫生—临床医学]