β-CD/碱体系还原间二硝基苯为氧化偶氮苯  

Reduction of 1,3-Dinitrobenzene to 3,3′-Dinitroazoxybenzene with β-Cyclodextrin/NaOH System

作　　者：郭爱玲[1] 尚卓镔[1] 金硕[1] 刘博[1] 

机构地区：[1]山西大学化学化工学院,山西太原030006

出　　处：《山西大学学报（自然科学版）》2005年第1期69-70,共2页Journal of Shanxi University(Natural Science Edition)

基　　金：国家自然科学基金(20372044)

摘　　要：在β-CD/碱(即β-环糊糊/NaOH)复合体系中,间二硝基苯还原为3,3′-二硝基氧化偶氮苯,反应温度55℃,产率为60%.文章研究了反应温度对产率的影响,实验表明:当反应温度超过70℃时,产率明显的下降,同时讨论了β-CD在反应中的作用.初步认为,β-CD具有疏水性空腔,与各种客体分子形成包结物,促进了间二硝基苯的选择性还原.该反应条件温和,操作简便,以水为反应介质,避免了有机溶剂对环境的污染.1,3-Dinitrobenzene could be reduced to 3,3′-dinitroazoxybenzene with β-cyclodextrin/NaOH system at 55 ℃ in 60 % yields.The relation between the reaction temperature and the yield was studied.The result indicated that the yield decreased obviously when the reaction temperature was more than 70 ℃.And the possible function of β-cyclodextrin was discussed.We believed tentatively that β-cyclodextrin with hydrophobic cavities could form inclusion complexes with a variety of guest molecules and promote selective reduction of 1,3-dinitrobenzene.The reactive conditions was moderate and the operation was simple and convenient.The synthetic method using water as the reaction medium may avoid the environmental pollution from organic solvent.

关 键 词：3 3′-二硝基氧化偶氮苯 Β-环糊精 还原 

分 类 号：O625[理学—有机化学]