颅底脑膜瘤骨增生与骨侵袭的相关性研究(英文)  

The relativity research of hyperostosis and tumor invasion in meningioma of the cranial base

作　　者：步星耀[1] 章翔[2] 尹志华[1] 张永福[1] 

机构地区：[1]河南省人民医院神经外科,河南郑州450003 [2]第四军医大学西京医院全军神经外科研究所,陕西西安710032

出　　处：《中华神经外科疾病研究杂志》2004年第6期504-506,共3页Chinese Journal of Neurosurgical Disease Research

基　　金：SupportedbyScienceFoundationofHenanProvinciaOutstandingYouth(99 0 7)

摘　　要：目的　探讨颅底脑膜瘤骨增生与骨侵袭的关系。方法　选取 4 9例需手术治疗的颅底脑膜瘤患者 ,术前均行CT检查 ,确定骨质增生的程度与部位 ;术中将肿瘤连同增生骨质进行病理检查 ,确定有无脑膜瘤细胞骨侵袭。结果　CT证实的 34例有骨增生的颅底脑膜瘤患者 ,进行增生骨质活检有肿瘤细胞侵袭的 31例。结论　颅底脑膜瘤骨增生与肿瘤细胞骨侵袭有关 ,手术时应予充分切除。Objective To investigate the relationship of hyperostotic changes and tumor invasion in meningioma of the cranial base.Methods Forty nine patients with meningioma of the cranial base underwent resection. Computed tomography such as preoperative radiographic evaluation was performed to identify the region and extent of hyperostosis. During the resection of the tumor, biopsies of tumor and its hyperostotic regions were sent out to identify whether there was bone invasion or not. Results Preoperative neuroradiological assessment identified that there were 24 patients with radiographic evidence of hyperostosis. Thirty one cases had tumor invasion identified by biopsy in all 34 cases with hyperostosis of cranial base meningioma identified by computed tomography.Conclusion Hyperostotic changes in meningioma of the cranial base are caused by bone invasion of the tumor histologically which needs resecting thoroughly.

关 键 词：脑膜瘤 颅底 骨增生 骨侵袭 

分 类 号：R739.41[医药卫生—肿瘤]