胃肠起搏治疗胃肠动力紊乱性疾病  

Gastrointestinal pacing for thetreatment of gastric motility disorders

作　　者：杨敏 房殿春 

机构地区：[1]重庆第三军区大学西南医院全军消华专科中心

出　　处：《中国医疗器械信息》2003年第4期14-17,共4页China Medical Device Information

摘　　要：胃肠动力紊乱性疾病十分常见,其发病率正呈上升趋势。目前对胃肠动力紊乱性疾病的治疗主要依赖促胃肠动力药物,但部分患者不能获得满意的疗效。另外,由于药物耗资的迅猛增加及药物相互作用,既加重了患者的经济负担,也引起了人们对药物不良反应及安全性的忧虑。故探索实用、经济、安全有效的新的治疗方法,有十分重要的意义。近年,采用胃肠起搏治疗胃肠动力紊乱性疾病日益受到关注。本文收集近期文献,结合我们自己的工作,从胃肠起搏的原理、方法、对胃肠动力的影响及在胃肠动力紊乱性疾病治疗中的应用诸方面进行综述。The morbidity of gastric motility disorder is increasing rapidly and reaching epidemic level, but its etiology is poorly understood and its treatment is unsatisfactory.The current treatment mainly relies on conventional prokinetic agents. However, some patients with motility disorder can not undergo a chronic treatment with prokinetic drugs because of the occurrence of severe adverse effects. In addition, tachyphylaxis may occur sooner or later and refractoriness to prokinetic agents is observed in a significant number of patients.The limited efficacy of drugs in gastric motility disorder has led investigators to examine the effect of gastric pacing on gastric emptying. In the wake of cardiac pacing ,some investigators hope that gastric pacing would be a new way to cure refractory gastric motility disorder.

关 键 词：胃肠动力紊乱性疾病 治疗中 胃肠起搏 患者 对药 常见 促胃肠动力药 增加 经济 依赖 

分 类 号：R57[医药卫生—消化系统] R259.7[医药卫生—内科学]