实验性肝硬化大鼠血液流变学特性的阶段性改变  

Hemorhelolgicai changes in different stages of experimental cirrhotic rats

作　　者：金峰[1] 张捷[1] 黄绪亮[2] 陈育尧[3] 余英豪[2] 张志坚[1] 

机构地区：[1]福州总医院消化内科 [2]解放军第一军医大学病理生理教研室 [3]解放军第一军医大学中西医结合研究所

出　　处：《福州总医院学报》2001年第3期158-159,共2页Journal of Fuzhou General Hospital

摘　　要：目的:探讨实验性肝硬化大鼠血液流变学特性的改变及意义。方法:对肝硬化大鼠不同时期的血液流变学参数进行检测。结果:随着肝脏病变的发展,大鼠血液流变学指标出现明显异常,主要表现在血粘度、血浆粘度、纤维蛋白原、血液还原粘度明显升高。结论:肝硬化大鼠血液流变学特性在肝脏病变的进程中存在显著的改变。Objective: To investigate the hemorheological changes and its significance in experimental cirrhotic rats. Methods: The paramental of hemorheology were tested in different stages of experimental cirrhotic rats.Results: The index of hemorheology of rats had abnormal changes, especially the viscosity of whole blood (WBV), plasma viscosity (Pv), fibrinogen (Fib) and WBRV were significantly increased in the course of cirrhosis.Conclusion: There are remarkable changes of hemorhelolgical characters in the course of cirrhosis in rats.

关 键 词：大鼠 血液流变学指标 改变 实验性肝硬化 肝脏病变 血粘度 血浆粘度 升高 纤维蛋白原 不同时期 

分 类 号：R575.2[医药卫生—消化系统] R743[医药卫生—内科学]