日本大耳白兔自发子宫内膜癌1例病理组织学及超微结构观察  

Histopathology And Ultrastructure of One Spontaneous Endometrial Carcinoma of Japanese Big-ear Rabbit

作　　者：张梅英[1] 时伟红[1] 王太一[1] 

机构地区：[1]中国医科大学实验动物学部,沈阳110001

出　　处：《中国实验动物学报》2000年第1期50-52,共3页Acta Laboratorium Animalis Scientia Sinica

摘　　要：本例日本大耳白兔自发子宫内膜癌属腺癌。光镜下癌细胞排列呈腺管状 ,腺腔大小不等 ,胞质少 ,核大 ,癌细胞已侵袭至肌层。电镜下癌细胞呈长椭圆形及不规则形 ,线粒体、粗面内质网较少或无 ,且二者均发生肿胀 ;某些细胞内可见少量初级溶酶体 ;细胞核大且大小不一 ,核膜多凹陷 ;核仁呈网眼状。This case of Japanese big-ear rabbit spontaneous endometrial carcinoma is adenocarcinoma .Under optical microscope, the cancer cells arranged as glandular ducts,the lumens of gland were of various size.The cells showed big nucleus and little cytoplasm. Cancer cells have invaded into the muscular layer. Under electron microscope we could see that the cancer cells were ellipitical or irregular with little mitochondrion and rough surfaced endoplasmic reticulum or even none.And both were tumefacient. A few primary lysosomes could be seen in some cancer cells.The nuclei were big and various in size .The nuclear membrane was pitted and nucleole was meshed.

关 键 词：子宫内膜癌 癌细胞 病理组织学 观察 超微结构 肿胀 细胞内 日本大耳白兔 胞质 发生 

分 类 号：Q959.483[生物学—动物学] R737.33[医药卫生—肿瘤]