急性白血病P-170和GSTπ的表达及临床意义  

The clinical implication of the expression of P-170 and GSTπ in acuted leukemia

作　　者：张春青[1] 徐从高[1] 张锑[1] 

机构地区：[1]山东医科大学附属医院肿瘤中心血研室,济南250012

出　　处：《临床肿瘤学杂志》1997年第1期19-21,共3页Chinese Clinical Oncology

摘　　要：用免疫细胞化学技术检测40例急性白血病患者P-170、GSTx的表达。结果:P-170阳性率为30％,初诊患者阳性率为26.7％,复发患者为50％,P-170阳性者CR率低,预后差;GST=阳性率为30％,初诊患者为20％,复发患者为75％,GSTx阳性者CR率低于阴性者:P-170和GST^t的表达在本组病例无相关性。The expression of P-170 and GSTπin 40 patients with acute leukemia were detected with monoclonal antibodies using APAAP method . The results showed that the positive rate of P-170 and GSTπwas 30% and 30% respectively. In the re-lapeed patients there was a higher rate for p-170,GSTπ(50% ,20% ) than that of newly diagnosed patients (26. 7% ,20%). The patients with positive P-170 showed poor response to chemotherapy and a low rate of complete remission. No correlation between expressions of P-170 and GSTπ.

关 键 词：P-170 患者 GSTΠ 表达 急性白血病 阳性率 初诊 复发 临床意义 CR 

分 类 号：R735[医药卫生—肿瘤] R733.71[医药卫生—临床医学]