MRI MnDPDP增强对原发性肝细胞癌的诊断价值  

Diagnostic Value of MnDPDP Enhanced MRI in Primary Hepatocellular Carcinoma

作　　者：汪登斌[1] 周康荣[2] 陈克敏[1] 陈憩[1] 展颖[1] 唐永华[1] 

机构地区：[1]上海第二医科大学瑞金医院放射科,200025 [2]复旦大学医学院中山医院放射科,200032

出　　处：《中国医学影像学杂志》2002年第1期1-4,共4页Chinese Journal of Medical Imaging

摘　　要：目的 :评估MRIMnDPDP增强不同延迟时间成像对原发性肝细胞癌的诊断价值。材料和方法 :对 3 6例HCCs行MRIMnDPDP增强研究。静脉滴注MnDPDP结束后 5min开始每隔 5min成像 1次 ,直至 40min ;第二天行延迟 2 4h成像。成像序列为SET1WI和FMPSPGRT1WI。对不同延迟时间图像的信噪比 (S/N)、对比度噪声比 (C/N)及病灶显示率进行比较研究。结果 :(1)不同延迟时间图像的S/N无统计学差异。 (2 ) 5～ 2 5min图像肝与HCC之间C/N高于 3 0min以后图像 (P<0 0 5 )。 (3 )病灶显示率和定性率均以延迟 2 4h最高 (92 7% ) ,但各组图像之间无显著差异。结论 :MnDPDP增强MRI的HCC显示率和定性率均以延迟 2Purpose: To evaluate the diagnostic value of MnDPDP enhanced MRI at different delayed times for primary hepatocellular carcinoma (HCC). Materials and Medthods: Thirty six patients of HCCs were investigated with MnDPDP enhanced MRI. The images were performed at every five minutes until 40 minutes after the end of intravenous infusion of MnDPDP, and the 24 hour delayed images were obtained the next day. The imaging sequences were T 1WI SE and T 1WI FMPSPGR. The S/N, C/N and the lesion detectability were compared for the images on the basis of delayed times. Results: (1) The S/N±S was not equal to each other according to the delayed times, but there was no statistical significance existed among them; (2)The C/N±S of the postcontrast images at 5～25 min were higher than that at and after 30 min (P<0 05); (3) The highest detection rate and charactersisation of HCCs were reached at 24 hour delayed images. Conclusion: The 24 hour delayed image of MRI enhanced with MnDPDP were the best one for detection and characterisation of HCCs.

关 键 词：MRI 显示率 原发性肝细胞癌 HCC 诊断价值 病灶 成像 图像 延迟 噪声比 

分 类 号：R735.7[医药卫生—肿瘤] R722.1[医药卫生—临床医学]