头颈部恶性淋巴瘤72例临床分析  

A clinical analysis on the Seventy-Two cases of malignant lymphoma in maxilloface and neck

作　　者：郑朝晖[1] 洪育明[1] 林泼水[1] 

机构地区：[1]福建医科大学第二临床医学院耳鼻咽喉科,362000

出　　处：《福建医药杂志》2004年第6期8-10,共3页Fujian Medical Journal

摘　　要：目的　探讨头颈部恶性淋巴瘤 (ML)的诊断方法和治疗措施。方法　对 72例经病理诊断的ML ,进行临床分期、病理组织类型分类 ,采用化疗、放疗、手术等综合治疗 5 2例 ,单一化疗 15例 ,单一放疗 5例。结果　 72例患者 1、 3、 5年生存率分别为 5 5 5 6 %、 38 89%、 2 0 83%。存活患者Ⅰ、Ⅱ期者占绝大多数 ,且多为恶性程度较低者 ,死亡患者中以Ⅲ、Ⅳ期为多。结论　诊断目的可包括肯定淋巴瘤的类型和决定病变累及的部位及范围。对颈部原因不明的淋巴结肿大反复活检以明确诊断。选择治疗方案的正确与否是治疗效果好坏的关键 ,综合治疗是最为有效的治疗手段 ,预后与组织类型、临床分期密切相关。Objective To explore the diagnosis and treatment of malignant lymphoma(ML)in maxilloface and neck.Methods After the pathological diagnosis,the classification of clinical stages and the affirmation of pathological tissue types,52 cases accepted systematic treatment,15 accepted chemotherapy alone and 5 radiotherapy only.Results The survival rates of the 72 patients who could survive for 1 year,3 years and 5 years more were 55.56%,38.89% and 20.83% respectively.Among survivals,most of them were at Ⅰ or Ⅱ stage,and their lymphoma was less serious;while among the deaths,most were at Ⅲ or Ⅳ clinical stage.Conclusions 1.The purpose of diagnosis should include the affirmation of lymphoma type and the pathological area.2.Repeated biopsy should be carried out if the mass is unclear in these areas.Chemotherapy combined with radiotherapy and operation is proved to be the most efficient therapeutic means.Meanwhile,the classification of clinical stage is important for the prognosis.

关 键 词：头颈部 恶性淋巴瘤 病理学检查 辅助化疗 放射治疗 

分 类 号：R739.91[医药卫生—肿瘤] R733.4[医药卫生—临床医学]