黏膜无色素性恶性黑色素瘤误诊原因分析  

Misdiagnositic analysis of mucosa-associated malignant melanomas

作　　者：王丽霞[1] 徐秒生[2] 殷卫东[1] 王晋芬[1] 

机构地区：[1]山西省肿瘤医院病理科,山西太原030013 [2]北京天坛医院病理科,北京010005

出　　处：《肿瘤防治杂志》2004年第5期533-534,共2页China Journal of Cancer Prevention and Treatment

摘　　要：为了探讨黏膜无色素性恶性黑色素瘤 (简称恶黑 )的病理形态特点及误诊原因 ,对 9例初诊时误诊的黏膜无色素性恶黑进行光镜观察及免疫组化染色。 9例中发生于鼻腔 2例 ,宫颈 1例 ,阴道 2例 ,肛管直肠 3例 ,道格拉氏窝 1例。初诊分别误诊为浆细胞瘤、淋巴瘤、垂体瘤、鳞癌、平滑肌肉瘤、腺癌 ,后经免疫组化染色确诊。初步研究结果提示 ,黏膜恶黑比较少见 ,且形态复杂 。To study the pathological characteristics and misdiagnostic causes of mucosa-associated malignant melanomas,nine cases of misdiagnosed mucosa-associated malignant melanoma were studied by light microscope and immunohistochemistry.Nine cases of mucosa-associated malignant melanoma were 2 from rhinal cavity and 1 from cervix,2 from vagina,3 from anus and rectum,1 from Douglas cavity.At first,these cases were misdiagnosed as plasmacytoma,lymphma,squamos cell carcinoma,leiomyosarcoma and adnocarcinoma.At last,correct diagnosis were made by immunohistochemical staining.Mucoa-associated malignat melanoma is rare tumor and its morphology is various.Without experience and without the help of immuno staining,it is very easy to make misdiagnosis.

关 键 词：黑色素瘤/诊断 误诊 免疫组织化学 

分 类 号：R730.4[医药卫生—肿瘤]