药物缓释制剂在抗PVR中的应用  

Application of sustained drug delivery system in treating PVR

作　　者：王弘[1] 祝肇荣[1] 

机构地区：[1]上海第二医科大学附属新华医院眼科,上海市200092

出　　处：《眼科新进展》2005年第1期83-85,共3页Recent Advances in Ophthalmology

摘　　要：抗增殖性玻璃体视网膜病变 (proliferativevitreo retinopathy,PVR)药物缓释制剂按其释药方式的不同可分为2大类 :一类为延缓释放制剂 ,如脂质体、微球。另一类即控释给药制剂 ,如各种植入体装置。近年来有学者还研制了一种新型的不需要载体的共药缓释系统。本文介绍了各种缓释制剂的特点及其在抗PVR中的应用 ,并评价它们各自的优缺点。As per the pattern of release,sustained drug delivery system for treating proliferative vitreoretinopathy (PVR) can be divided into two groups.One is the prolonged-release system,such as liposome,microsphere.The other is the controlled-release system,such as various kinds of implants.Recently a novelcodrug system without extra carrier has been developed.This article introduces the character of these devices and their appliance in preventing PVR and evaluate their respective advantage and disadvantage also.

关 键 词：增殖性玻璃体视网膜病变 玻璃体 缓释制剂 

分 类 号：R774.1[医药卫生—眼科]