首次无复发间期在浅表膀胱癌患者中的远期预后价值  

Long-term Prognostic Value of the First Recurrence-free Period in Patients with Superficial Bladder Cancer

作　　者：曾福华[1] 杨土保[2] 江勃年[1] 付忠平[1] 韩帷青[1] 谭春祈[1] 唐卫[1] 

机构地区：[1]湖南省肿瘤医院腹外一科,湖南长沙410006 [2]中南大学公共卫生学院流行病与卫生统计学系,湖南长沙410008

出　　处：《医学临床研究》2004年第11期1304-1306,1310,共4页Journal of Clinical Research

摘　　要：【目的】评价首次无复发间期 (recurrence freeperiod ,RFP)在浅表膀胱癌患者中的远期预后价值。【方法】利用回顾性队列研究将 6 7例复发的浅表性膀胱移行细胞癌患者按RFP分组 ,RFP≤ 4 0个月者 34例为A组 ,RFP >4 0个月者 33例为B组 ,比较两组间的预后影响因素的均衡性及远期预后指标间的差异。【结果】在影响预后的因素中 ,除首次无复发间期外 ,其他影响预后的因素在A、B两组之间的分布并无差别 ;而B组的进展率及转移率均低于A组 ,B组的膀胱保全率及肿瘤特异生存率均高于A组 ,A组出现进展的风险、膀胱丧失的风险、出现转移的风险、肿瘤特异死亡的风险均高于B组 ,经统计学分析具有统计学意义。ObjectiveTo evaluate the long-term prognostic value of the first recurrence-free period (RFP) in patients with superficial bladder cancer (SBC).Sixty-seven patients with recurrent superficial transitional cell cancer of bladder were divided retrospectively into two groups:①Group A, 34 patients with RFPs ≤40 months ; and ②Group B, 33 patients with RFPs > 40 months. The differences in the balance of prognostic factors and long-term prognostic data were compared between both groups.Except the first RFP, there were no differences in the other prognostic factors between Group A and Group B. Howerver, the rates of tumor progress and metastasis in Group B were lower than in Group A ; whereas the rates of bladder preservation and tumor specific survival in Group B were higher than in Group A. Furthermore, the risks of tumor progress and bladder loss as well as the risks of metastasis and tumor specific death in Group A increased as compared to those in Group B ; these differences between both groups revealed statistical significance.[Conclusion]The first RFP can be served as an effective index to evaluate the long-term prognosis in patients with SBC.

关 键 词：膀胱肿瘤 预后 

分 类 号：R737.14[医药卫生—肿瘤]