小儿原发性胃肠道非霍奇金淋巴瘤(附12例报道及文献复习)  

Pediatric primary gastrointestinal non-hodgkin lymphoma (A clinical report of 12 cases and literature review)

作　　者：郑宝燕[1] 王华[2] 朱永湘[2] 谭国钳[3] 

机构地区：[1]广东药学院儿科教研室,广州510224 [2]广东药学院外科教研室,广州510224 [3]广州市红十字会医院普外科

出　　处：《胃肠病学和肝病学杂志》2004年第6期645-647,共3页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的 探讨小儿原发性胃肠道非霍奇金淋巴瘤的临床特征及误诊因素。方法 回顾性分析12例小儿原发性胃肠道非霍奇金淋巴瘤的临床资料。结果 本组12例,其中男性9例,女性3例。年龄5-14岁。病期:一期4例,二期6例,三期2例。误诊11例。全组病人均行手术治疗,手术切除率100％(含姑息切除2例),部分病人进行了术后化疗。预后:一、二期优于第三期;低度恶性者优于中、高度恶性者。结论 本病缺乏特异的症状和体征,早期诊断困难,加上对该病缺乏认识是临床误诊的主要原因。本病的预后与其病期,病理生物学和治疗措施密切相关。Objective To analysis the clinical characteristics and the misdiagnosis factors of the PGI-NHI. Methods Twelve cases with PGI-NHL were reviewed retrospectively. Results Among 12 cases,9 were male and 3 were female. Age arranges from 5 to 14 year old. Clinical stage:4 cases were in stage 1,6 cases were in stage Ⅱ ,2 cases were in stage Ⅲ . 11 cases were misdiagnosed. All of these patients underwent surgical operation cures, part of these patients proceeded chemotherapy. The prognosis of the patients whose clinical stage were Ⅰ or Ⅱ was obviously better than that of stage Ⅲ , and the lower grade malignant group was obviously better than that of the higher grade malignant group. Conclusion The symptom of this disease is unspecific, diagnosis is difficult in the earlier period, and lack comprehension of the disease is the main reason leading to clinical misdiagnosis. Prognosis of GPI-NHL relate closely with its clinical stage, pathophysiology and the treatments measure.

关 键 词：原发性 非霍奇金淋巴瘤 胃肠道 病期 病人 文献复习 小儿 缺乏 病理生物学 

分 类 号：R735[医药卫生—肿瘤] R733[医药卫生—临床医学]