复合氨基酸注射液18-3224治疗营养不良低蛋白血症的临床观察  

A Clinical Study of the Treatment of Malnutrition and Protein Deficiency with Amino Acid Compound 18-3224

作　　者：周际安[1] 王家(马龙)[2] 易粹琼[3] 周永斌[4] 罗霞[1] 章弘 曾繁典[1] 

机构地区：[1]同济医科大学临床药理学研究室 [2]同济医科大学附属同济医院内科 [3]同济医科大学附属协和医院内科 [4]中国人民解放军军工医院,430030

出　　处：《同济医科大学学报》1993年第2期104-107,共4页Acta Universitatis Medicinae Tongji

摘　　要：复合氨基酸注射液18-3224系一种新型等渗、供外周静脉注射用的氨基酸制剂。74例继发性营养不良、低蛋白血症患者随机分两组,50例应用本品每日 500 ml,连续应用 2周,患者血浆总蛋白、白蛋白及血清运铁蛋白浓度分别由 59.46±8.54 g/L、32.99±1.93 g/L、1.72±0.58g/L,增至63.14±8.72 g/L、35.61±3.53 g/L、2.15±0.79 g/L。血清游离氨基酸浓度不同程度增加。日本产相同制剂 Moriamin-N 以同法治疗24例同类型患者亦有相似效应。两组总有效率分别为72％和71％,差异无显著性意义。The injection of amino acid compound 18-3224 is a new isosmotic amino acid solution for peripheral intravenous administration. 74 patients with malnutrition and protein deficiency were divided randomly into two groups, group A and group B. 50 patients in group A were treated with 500 ml of injection of amino acid compound 18-3224 daily during the treatment period of 14 days. The total plasma protein, albumin and serum transferrin concentration were 59.46±8.54 g/L, 32.99±1.93 g/L, 1.72 ±0.58 g/L respectively before treatment and rose to 63.14±8.72 g/L, 35.61±3.53 g/L, 2.15 ±0.79 g/L respectively at the end of treatment. Serum free amino acid concentration also increased in varying degrees.24 patients with similar clinical conditions treated with the same dosage of moriamin-N served as controls. The results of treatment were found similar in both groups. The total effective rate of injection of amino acid compound 18-3224 and moriamin-N is 72% and 71% respectively.

关 键 词：复合氨基酸 针剂 营养不良 氨基酸 

分 类 号：R591.2[医药卫生—内科学]