慢性胰腺炎294例的病因学及临床诊治  

Etiology, diagnosis and treatment of chronic pancreatitis: an analysis of 294 cases

作　　者：陈浮[1] 李兆申[1] 李淑德[1] 王洛伟[1] 许国铭[1] 

机构地区：[1]中国人民解放军第二军医大学长海医院消化内科,上海市200433

出　　处：《世界华人消化杂志》2004年第12期2829-2832,共4页World Chinese Journal of Digestology

摘　　要：目的:研究我国慢性胰腺炎的相关因素及诊治特点方法:回顾分析长海医院近10 a确诊为慢性胰腺炎的294例住院患者,调查其相关病因、诊断方法及治疗措施. 结果:在294例患者中,胆源性89例(30.3%),酒精性84 例(28.6%),其他病因包括腹部手术后、胰腺外伤、胰管先天异常、自身免疫病、先天因素以及特发性等,均较少见.大部分患者表现为反复发作性腹痛,少数伴有脂肪泻及体重减轻等症状.49例患者通过组织学检查确诊,其他均通过影像学检查及BT-PABA试验诊断.大部分患者(81.0%)经非手术治疗症状缓解. 结论:慢性胆道系统疾病仍是我国慢性胰腺炎的主要致病因素,但其比例明显下降,而酒精性慢性胰腺炎明显增多.影像学检查在慢性胰腺炎诊断中具有重要作用,非手术治疗是目前治疗慢性胰腺炎的主要方法.AIM: To investigate the associated factors, diagnosis and treatment of chronic pancreatitis in Shanghai, China. METHODS: Two hundred and ninety four patients with confirmed chronic pancreatitis in Changhai Hospital were retrospectively studied, including investigation of their associated etiological factors, diagnostic and therapeutic methods. RESULTS: Of all the 294 patients, there were 89 with biliary chronic pancreatitis (30.3%) and 84 with alcoholic pancreatitis (28.6%). The rest included idiopathic chronic pancreatitis, abnormity of pancreatic duct, hereditary pancreatitis and autoimmune pancreatitis. The most common symptom of chronic pancreatitis was abdominal pain. A few patients were accompanied by steatorrhoea and decrease body weight. Forty-nine patients were diagnosed by histopathology. Others were diagnosed by imaging procedures. The positive rate for imaging diagnosis was 88.0% on average. Most patients suffered less after non-operation therapies. CONCLUSION: Biliary diseases are still the most common etiological factors of chronic pancreatitis, but its rate has significantly decreased in Shanghai. Meanwhile, the rate of alcoholic chronic pancreatitis is increasing gradually. Imaging procedures play the most important role in diagnosis, and non-operation therapies are the main methods to treat chronic pancreatitis.

关 键 词：慢性胰腺炎 病因学 治疗 诊断 

分 类 号：R576[医药卫生—消化系统]