腔隙性脑梗死患者血压变化与预后的关系分析  

Relationship between the changes of blood pressure and outcome in patients with lacunar infarct

作　　者：王运良[1] 刘滨[1] 刘萍[1] 耿爽[1] 石传江[1] 熊晖[1] 

机构地区：[1]解放军第148医院,山东周村255300

出　　处：《山东医药》2005年第1期8-9,共2页Shandong Medical Journal

摘　　要：目的　探讨腔隙性脑梗死患者 2 4小时血压变化与预后的关系。方法　对 91例腔隙性脑梗死患者平均随访 3年 ,按不同预后分为三组 ,A组 4 1例 ,随访期间无再发生脑血管病和痴呆表现 ;B组 2 3例 ,有痴呆和静止性损害表现 ,包括腔隙性和弥漫性脑白质损害 ;C组 2 7例 ,有进展性脑梗死表现。另设 2 0例为对照组 (健康体检正常者 )。四组每年均进行一次头颅 MRI检查和血压监测。结果　A组 2 4小时、白天收缩压 ,2 4小时、白天及夜间舒张压均明显高于首次 ;B组明显低于首次 ;C组 2 4小时和白天收缩压均低于首次 ;对照组血压无明显变化。结论　腔隙性脑梗死预后良好者血压趋于升高 ,进展性梗死和痴呆者血压降低。Objective To investigate blood pressure(BP) changes throughout a 24-hour period in lacunar infarct patients with different outcomes.Methods Twenty control subjects and 91 patients with lacunar infarct were followed up 3 years,and were divided into three groups according to their outcomes:group A,41 patients with a fair outcome without any cerebravascular attack or dementia;group B,23 patients with silent lesions and dementia,which included lacunar and diffuse white lesions;group C,27 patients who developed symptomatic infarct.Results In group A,the second measurement were significantly higher than the first for 24-hour systolic BP,daytime BP,24-hour diastolic BP,daytime diastolic BP,nighttime diastolic BP.In group B,the second measurement were significantly lower than the first for 24-hour systolic BP,daytime BP,24-hour diastolic BP and daytime diastolic BP.In group C,the second measurement were significantly lower than the first for 24-hour systolic BP and daytime BP.Conclusion BP tends to elevate in patients with a fair outcome.In contrast,BP tends to decrease in those who developed dementia and symptomatic infarct.

关 键 词：腔隙性脑梗死 预后 血压变化 首次 患者 痴呆 对照组 关系分析 表现 平均 

分 类 号：R743.33[医药卫生—神经病学与精神病学] R544.1[医药卫生—临床医学]