肝硬化并发肝癌病例中的肝动脉峰值流速与阻力指数的动态变化  

The dynamic change of the flow peak velocity and the resistance index of hepatic artery in patients of liver cirrhosis with hepatic carcinoma

作　　者：董磊[1] 陆建明[1] 邵明焕[1] 叶萍[1] 蒋继东[1] 

机构地区：[1]江苏省常熟市第二人民医院功能科,第二军医大学在读博士215500

出　　处：《上海医学影像》2004年第4期256-257,260,共3页Shanghai Medical Imaging

摘　　要：目的探讨超声检测肝动脉血流峰速度(Vmax)与阻力指数(RI)的动态变化早期诊断结节性肝癌(肿块的直径在1cm以下)的临床应用价值;方法选取临床诊断为肝硬化的乙肝患者150例,应用超声定期检查肝动脉的Vmax、RI,直至患者被影像检查及临床诊断为结节性肝癌,计算Vmax、RI的动态变化值⊿Vmax、⊿RI,进而计算⊿Vmax、⊿RI动态变化的百分比;结果从肝硬化发展为结节性肝癌的23例患者的肝动脉Vmax、RI初检至癌变前无明显变化(P>0.05),出现结节性肝癌时飞跃性增加或降低(P<0.05),且⊿Vmax%、⊿RI%的95%参考值范围与癌变前的测值范围无重叠;结论肝动脉Vmax、RI等血流参数的动态变化是早期诊断结节性肝癌的可靠参数。Objective To seek the clinical significance of the dynamic change of the flow peak velocity(Vmax) and the resistance index(RI) of hepatic artery in diagnosing the early stage nodular hepatic carcinoma (the diameter of tumour less than 1cm ) by ultrasonography. Methods We selected 150 patients with liver cirrhosis and measured the Vmax and RI of hepatic artery till hepatic carcinoma was diagnosed with imaging modalities. The ⊿Vmax?⊿RI and percentage of ⊿Vmax?⊿RI(⊿Vmax%?⊿RI%) were compared. Results The ⊿Vmax%?⊿RI% of hepatic artery in 23 patients with nodular hepatic carcinoma increased or decreased significantly compared with before (P<0.05),and 95% reference value of ⊿Vmax% and ⊿RI% was not serried with measuring value. Conclusions The dynamic change of Vmax and RI of hepatic artery is a credible parameter for diagnosing the early stage of nodular hepatic carcinoma.

关 键 词：肝癌 肝动脉 RI 结节性 肝硬化 阻力指数 动态变化 峰值流速 患者 临床诊断 

分 类 号：R735[医药卫生—肿瘤] R575.2[医药卫生—临床医学]