Bestimmung des regionalen Blutvolumens (rBV) in Meningeomen: Vergleich von Echoplanar-und Gradientenechosequenzen  

作　　者：吴仁华 Roland Bruening Christian Berchtenbreiter Jügen Weber 郎志谨 Maximilian Reiser 

机构地区：[1]Abteilung für Radiologie,Medizinische Fakultt der Universitt Shantou,Shantou 515041,China,Institut für Diagnostische Radiologie,Klinikum Grophadern,Ludwig-Maximilians-Universitt,München 81377,Germany [2]Institut für Diagnostische Radiologie,Klinikum Grophadern,Ludwig-Maximilians-Universitt,München 81377,Germany [3]Abteilung für Radiologie,Medizinische Universitt Dalian,Dalian 116011

出　　处：《Journal of Huazhong University of Science and Technology(Medical Sciences)》2004年第6期610-614,共5页华中科技大学学报（医学英德文版）

基　　金：grantstheFriedrichBaurInstitute,GemanyandtheNationalNaturalScienceFoundationofChina(No.30270379and30310103211)

摘　　要：Summary: The purpose of this study was to evaluate relative regional blood volume (rCBV) in meningioma and compare the utility of reconstruction using both gradient-echo sequence and echo-planar-imaging (EPI) sequence.Eighteen patients with meningiomas were studied on a Siemens 1.5-T scanner. During the gradient-echo sequence (n=12) and EPI sequence (n=6), a bolus ^(0.2 mmol/kg) of Gd-DTPA was injected mechanically with a flow rate of 5 ml/second. Image processing of dynamic data was performed on a pixel-by-pixel basis. The ratio of tumor rCBV/gray matter rCBV was 3.01±1.18 (3.07 ± 1.39 in gradient sequence and 2.84 ± 0.94 in EPI sequence). The ratio of gray matter/ white matter as the reference tissue had a mean of 2.79 ± 0.76 using the FLASH sequence, and a mean of 3.04 ± 1.31 using EPI. These differences were not statistically signifcant (P>0.5, t-test). According to the ratio of tumor rCBV/gray matter rCBV, a mean value, 14.5 ml/100 g, of rCBV in meningiomas was calculated. Compared with gray matter, increased inhomogeneous rCBV was observed in meningioma. Based on the two different sequences, no bias can be observed in our rCBV reconstruction.

关 键 词：magnetic resonance imaging MENINGIOMA blood volume 

分 类 号：R739.45[医药卫生—肿瘤]