左旋卡尼汀治疗慢性充血性心力衰竭临床疗效观察  

Clinical Efficiency Observation of L-carnitine in Treatment of Patients with Chronic Congestive Heart Failure

作　　者：周瀛[1] 白春锦[1] 

机构地区：[1]沈阳医学院附属第二医院心内科,辽宁沈阳110002

出　　处：《沈阳医学院学报》2004年第4期228-229,共2页Journal of Shenyang Medical College

摘　　要：目的 :观察左旋卡尼汀 (L carnitine ,L CN )治疗慢性充血性心力衰竭 (CHFF)患者的临床疗效。方法 :选择住院的 96例慢性充血性心力衰竭患者 ,随机分为左旋卡尼汀治疗组和对照组。对照组 (48例 )给予洋地黄、利尿剂、血管扩张剂、ACEI或 β受体阻滞剂等常规药物 ;L CN组 (48例 )在常规治疗的基础上加用L CN治疗 ,10d为一疗程。结果 :L CN组心功能改善的临床显效率 (43.8% )和总有效率 (91.7% )均较对照组 (2 5 .0 %和 70 .8% )显著提高 (P <0 .0 5 ) ,且无不良反应出现。结论 :用L CN辅助常规药物治疗慢性充血性心力衰竭是一种安全有效的方法。Objective:To observe the effect of L-carnitine (L-CN) in the treatment of chronic congestive heart failure (CHF).Methods:Ninety-six cases with chronic CHF randomly received routine treatment (digitalis, diuretics, vasodilator, ACE I or βblocker) or L-CN (3.0 g/d , 10 d) with routine therapy.Results: The therapeutic efficiency of L-CN group and control group were 91 7% and 70 8% (P<0.05), respectively. No adverse reactions related to the drug were observed. Conclusion:L-CN with routine therapy might be a safe way to the treatment of chronic CHF.

关 键 词：治疗 慢性充血性心力衰竭 左旋卡尼汀 对照组 CN 临床疗效观察 患者 结论 方法 目的 

分 类 号：R541[医药卫生—心血管疾病] R735.7[医药卫生—内科学]