老年人晚期胰腺癌立体定向放射治疗的临床研究  

Stereotactic radiotherapy in elderly patients with advanced pancreatic cancer

作　　者：丁田贵[1] 尹立杰[1] 彭兆祥[1] 

机构地区：[1]大连大学医学院附属中心医院放射治疗科,116033

出　　处：《中华老年医学杂志》2005年第2期97-99,共3页Chinese Journal of Geriatrics

摘　　要：目的　探讨老年人晚期胰腺癌立体定向放射治疗的近期疗效。　方法　对我院采用立体定向伽玛射线放射治疗的 6 5例老年晚期胰腺癌患者的临床资料及随访情况进行回顾性分析。　结果　放射治疗后疼痛缓解或消失 5 3例 (92 9% ) ,体重增加≥ 7%者 19例 (2 9 2 % ) ,卡氏评分较入组前上升超过 2 0分以上者 2 8例 (43 1% ) ,临床受益反应率为 6 1 2 % ;完全缓解 (CR) 4例 (7 0 % ) ,部分缓解 (PR) 2 1例 (36 8% ) ,CR +PR为 2 5例 (43 8% )。中位生存时间 9 3个月。　结论　老年人晚期胰腺癌的立体定向伽玛射线放射治疗近期疗效显著 ,是一种安全、可靠的治疗方法。Objective To evaluate the curative effect of stereotactic radiotherapy in pancreatic cancer in the elderly. Methods Retrospectively analyzed 65 elderly patients with pancreatic cancer were treated with stereotactic radiotherapy. The ages of patients were 60 to 86, with mean age of 71 2. The numbers of treatment were 8 to 12 times according to the tumor size and patients condition Fractional dose were 3 to 6 Gy, total dose were 32 to 54 Gy. The curve of isodose was 50%～80% Results The patients average alive time was 9 3 months after stereotactic radiotherapy The clinical benefit response rate was 61 2%. The CR+PR was 38 4% Conclusions The stereotactic radiotherapy is safe and effective method for treating elderly pancreatic cancer

关 键 词：老年人 晚期胰腺癌 立体定向放射治疗 近期疗效 PR 缓解 临床研究 结论 伽玛射线 上升 

分 类 号：R735.9[医药卫生—肿瘤] R737[医药卫生—临床医学]