精神分裂症住院患者使用抗精神病药现状  

Survey of antipsychotic drug use among schizophrenic inpatients

作　　者：毛佩贤[1] 王智民[1] 汤宜朗[2] 蒋锋[1] 蔡焯基[1] 

机构地区：[1]首都医科大学附属北京安定医院,100088 [2]美国耶鲁大学精神病学系

出　　处：《临床精神医学杂志》2005年第1期1-2,共2页Journal of Clinical Psychiatry

基　　金：北京市重点扶持学科经费及首都医学发展科研基金资助 (首都ZD199816)

摘　　要：目的 :调查精神分裂症住院患者抗精神病药使用现状。　方法 :样本采取整群入组 ,横断面调查方法 ,符合国际疾病分类第 10版精神分裂症诊断标准的患者 ,共 5 0 3例 ,调查其用药情况。　结果 :临床药物治疗以单一用药为主 (占 90 .9% ) ,氯氮平使用比例较高 (占 30 .2 % ) ;首次发病及病程短于 5年的患者使用新型抗精神病药相对较多 (分别为 2 0 .7%及 31.5 % )。　结论 :传统抗精神病药物仍为目前的主流治疗药 ,使用新型抗精神病药所占比例远低于发达国家。临床医生在选择氯氮平时 ,对躯体情况缺乏关注。Objective:To investigate current antipsychotic drug use among schizophrenic patients. Method:Cross-sectional survey method was used for this study,503 inpatients met the ICD-10 diagnostic criterion of schziophrenia were investigated and assessed with the drug treatment. Results:Most patients (90.9%) were on mono-therapy of antipsychotic drugs.The frequency of clozapine use was relative high (30.2%).Patients of first episode and with less than 5 years course were more likely be treated with new atypicals (20.7% and 31.5% respectively). Conclusion:Conventional antipsychotics are current mainstream treatment in schizophrenia, and the percentage of patients received new atypical antipsychotics are lower in China than in developed countries. Clinicians lack of attention to physical conditions when they use clozapine.

关 键 词：精神分裂症 抗精神病药 氯氮平 

分 类 号：R749.3[医药卫生—神经病学与精神病学]