左心房黏液瘤与肺动脉高压及心功能不全的相关性研究——附30例报告  

The relationship between heart failure, pulmonary hypertension and weight of left atrial myxoma.

作　　者：张凤伟[1] 吴树明[1] 邢西忠[2] 张秀辉[2] 李镇[2] 

机构地区：[1]山东大学齐鲁医院心外科,250012 [2]山东临沂市人民医院,276003

出　　处：《新医学》2005年第2期70-72,共3页Journal of New Medicine

摘　　要：目的探讨左心房黏液瘤瘤体大小与肺动脉高压及心功能不全之间的相关关系。方法按纽约心脏学会心功能分级标准,把30例左心房黏液瘤病人分为Ⅰ级、Ⅱ级、Ⅲ级、Ⅳ级4组,分别在体外循环建立前和撤除体外循环管道后测量其肺动脉压,并在黏液瘤切除后称量瘤体重量,分析瘤体重量和肺动脉高压、心功能不全的关系。结果心功能Ⅱ级、Ⅲ级和Ⅳ级患者肺动脉高压的发生率明显大于心功能Ⅰ级患者(均为P<001)。心功能Ⅰ级、Ⅱ级、Ⅲ级、Ⅳ级患者的瘤体重量分别为(21±9)g、(29±10)g、(40±10)g、(73±19)g;肺动脉高压的发生率分别为0、36%、6/6、5/5。切除黏液瘤后,心功能Ⅱ级、Ⅲ级、Ⅳ级患者的平均肺动脉压分别由术前的(36±12)kPa、(45±13)kPa、(64±09)kPa降为术后的(24±09)kPa、(28±12)kPa、(31±11)kPa(均为P<001)。结论左心房黏液瘤的瘤体大小与患者的肺动脉高压及心功能不全的程度密切相关。Objective: To investigate the relationship between heart failure, pulmonary hypertension and weight of left atrail myxoma. Methods: Thirty patients with left atrail myxoma were divided into 4 groups according to New York Heart Association (NYHA) function class. The pulmonary artery pressure value was measured before initialization of cardiopulmonary bypass (CPB) and after termination of CPB, respectively. The tumor weight was recorded immediately after myxoma was excised. Results: The incidence of pulmonary hypertension in the patients with NYHA function class Ⅱ,Ⅲ and Ⅳ increased significantly than that in the patients with NYHA function classⅠ(P<0.01).The weight of tumor in the patients with NYHA function class Ⅰ,Ⅱ,Ⅲ and Ⅳ was (21±9)g,(29±10)g,(40±10)g,(73±19)g, respectively. The incidence of pulmonary hypertension was 0,36%,6/6,and 5/5 respectively. The pulmonary arterial pressure in class Ⅱ、Ⅲ and Ⅳ reduced respectively from (3.6±1.2)kPa,(4.5±1.3)kPa,(6.4±0.9)kPa preoperatively to (2.4±0.9)kPa, (2.8±1.2)kPa,(3.1±1.1)kPa postoperatively (P<0.01,P<0.01,P<0.01). Conclusion: These results indicate that close positive correlation between the weight of the tumor and the pulmonary hypertension and heart failure exist in patients with left atrial myxoma. [

关 键 词：肺动脉高压 瘤体 左心房黏液瘤 心功能不全 患者 肺动脉压 相关性研究 重量 管道 纽约 

分 类 号：R732.1[医药卫生—肿瘤] R541[医药卫生—临床医学]