1996～2002年大连地区先天性唇腭裂的调查研究  

Study and Analysis of Cleft Lip and/or Cleft Palate in Dalian: 1996～2002

作　　者：黄海涛[1] 王如[1] 丛蔚[1] 董海燕[2] 

机构地区：[1]大连医科大学附属第一医院口腔颌面外科,辽宁大连116011 [2]大连市妇产医院产科

出　　处：《口腔医学研究》2005年第1期82-84,共3页Journal of Oral Science Research

摘　　要：目的:了解大连地区唇腭裂发生情况,比较综合征性唇腭裂与非综合征性唇腭裂的流行病学差异。方法: 对大连地区38家县级以上助产医院1996～2002年期间的新生儿的出生缺陷资料进行整理,对263例非综合征性 及38例综合征性唇腭裂病例进行回顾性分析。结果:1996～2002年大连地区非综合征性唇腭裂发病率为12.0/ 万;综合征性唇腭裂发病率为1.7/万。在66例总唇裂患儿中,有4例伴发全身其它畸形,占6.1%;在53例总腭裂 患儿中,有8例伴发全身其它畸形,占15.1%。结论:腭裂伴发其它畸形的发生率要高于唇裂伴发其它畸形;腭裂 伴发其它畸形,男性发病多于女性;非综合征性与综合征性唇腭裂在患儿体重及转归上有显著性差异。Objective: To study incidence of cleft lip and/or cleft palate in Dalian and to find out the difference between nsCLP and CLP. Methods: From 1996 to 2002, data were collected from 38 hospitals. Result: From 1996 to 2002, the incidence of nsCLP in Dalian was 12.0/10 000; the incidence of CLP was 1.7/10 000. There were 4 cases who suffered from other deformations at a proportion of 6.1% in all 66 cleft lip patients; there were 8 cases who suffered from other deformations at a proportion of 15.1% in all 53 cleft palate patients. Conclusion: It is more likely for a patient with cleft palate to suffer from other deformations than the one with cleft lip. It is more likely for male than female to suffer from cleft palate with other deformations. There are significant difference in the incidence of the body weight, and the death rate between nsCLP and CLP.

关 键 词：唇腭裂 发病率 死亡率 

分 类 号：R782.2[医药卫生—口腔医学]