复方溶石剂一号的效果及安全性评价  

Studys on the efficacy and safety of compound lithontripic No. 1

作　　者：张虹[1] 

机构地区：[1]武警医学院附属医院特诊科,天津300162

出　　处：《药学实践杂志》2005年第1期24-27,共4页Journal of Pharmaceutical Practice

摘　　要：目的:评价复方溶石剂一号的效果及毒副作用。方法:观察各溶石剂一号在37℃的溶石效果;观察溶石剂一号对家兔结膜的刺激性及对器官和血液生化指标的影响;并通过手术观察其在狗体内的溶石情况。结果:复方溶石剂一号在体外和体内均较阳性对照药效果好,对家兔的结膜基本无刺激性,对器官和血液生化指标的影响较阳性对照药小。结论:复方溶石剂一号是一种优良的溶石剂。Objective:To evaluate the efficacy and the side effect of compound lithontripic No. 1. Method: The lithontripic efficacy of the compound lithontripic No. 1 at 37℃ and the thrill to rabbits eyes were observed. The effect of lithontripic No. 1 to the apparatus and hematological index were researched. The lithontripic effect on postoperative dog was also observed. Results: The effect of Lithotripic No. 1 is better than the positive controlled drug in vitro and in vivo. The lithontripic No. 1 hadn't any thrill to rabbit's eyes and the effect on apparatus and hematological was less than the positive controlled drug. Conclusion: The lithintripic No. 1 is a kind of good compound in treatment of gallstone.

关 键 词：溶石剂 胆结石 药物治疗 

分 类 号：R575.62[医药卫生—消化系统]